Journal of neuroimaging : official journal of the American Society of Neuroimaging
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The purpose of this study was to reevaluate the usefulness of relative maximum signal drop (rMSD), as compared to relative cerebral blood volume (rCBV) and cerebral blood flow (rCBF), in dynamic susceptibility contrast magnetic resonance imaging (MRI). ⋯ The authors conclude that rMSD is as useful as rCBF under a variety of pathophysiological conditions, whereas in conditions with normal mean transit time, such as brain tumors, rMSD provides equivalent blood volume information to rCBV. The simplicity of rMSD maps could lead to the increased use of perfusion-weighted MRI.
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Case Reports
A case study of hemispatial neglect using finite element analysis and positron emission tomography.
The authors present a patient who developed transient hemispatial neglect following surgical drainage of a large right frontotemporal arachnoid cyst. As symptoms evolved in parallel with brain shift over the subsequent months, the authors hypothesized that the disorder was associated with the appearance of mechanical stresses in the cerebral mantle. ⋯ The authors conclude that brain deformation was a contributing factor in the reversible neglect syndrome by compromising the normal flow of blood and/or the deactivation of subcortical circuits of the parietal lobe.
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Case Reports
Development of a posterior fossa cavernous malformation associated with bilateral venous anomalies: case report.
Venous angiomas (VAs) and cavernous malformations (CMs) are common cerebrovascular malformations. Frequently, these lesions are found in close proximity. The interrelationship between VAs and CMs has not yet been adequately defined. ⋯ The sequential imaging suggests a causal relationship between VAs and some CMs. Furthermore, the detailed MRI permitted radiosurgical treatment of these CMs. The occurrence of de novo CMs adjacent to VAs on future imaging studies in other patients may help confirm the etiology of at least a subset of CMs.
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Involvement of the brain is one of the most important complications of Behçet's disease, but its diagnosis is difficult because of the lack of effective imaging tools. Therefore, technetium-99m ethyl cysteinate dimer (Tc-99m ECD) single-photon emission computed tomography (SPECT) of the brain was used to detect abnormal regional cerebral blood flow in patients with neuro-Behçet's syndrome (NBS). ⋯ The parietal lobes were the most common areas with hypoperfusion lesions. Tc-99m ECD brain SPECT is a more sensitive and useful tool than brain MRI for detecting hypoperfusion areas of the brain in NBS patients.