Enfermedades infecciosas y microbiología clínica
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Refractory hypotension is the main cause of death of patients with septic shock. It has been shown that an excessive release of NO is responsible for the sepsis-induced hypotension and vascular hyporeactivity. ⋯ Randomized clinical trials have shown that the administration of inhibitors of NO synthesis to patients with septic shock is associated with a greater incidence of shock resolution, without significant adverse effects. The recent discovery of the different biological functions of NO, both under normal and inflammatory conditions, has allowed the development of new concepts about the pathophysiology of septic shock, and has provided the bases to design novel therapeutic strategies for the treatment of septic shock, based on the inhibition of NO synthesis.
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Enferm. Infecc. Microbiol. Clin. · Aug 1997
[Intensive care for patients with the human immunodeficiency virus].
HIV infection is of special importance in Spain, occasionally requiring the use of intensive care units (ICU) in the management of these cases. ⋯ Respiratory failure produced by Pneumocystis carinii or by other germs is the most frequent cause for ICU admission of patients with HIV infection. Renal failure, lymphopenia, and hypoalbuminemia are predictors of mortality in almost 50% of the cases.
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Enferm. Infecc. Microbiol. Clin. · Jun 1997
[Risk factors and length of stay attributable to hospital infections of the urinary tract in general surgery patients].
Urinary tract infection (UTI) is the second frequent site of infection in surgical patients; nevertheless, its study has been frequently neglected. The main objective of this report is the analysis of risk factors for ITU in general surgery. ⋯ The use of closed systems for urethral catheters is cost-saving.