Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular
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Rev Bras Cir Cardiovasc · Oct 2013
Reversible pulmonary trunk banding: IX. G6PD activity of adult goat myocardium submitted to ventricular retraining.
Increased glucose 6-phosphate dehydrogenase activity has been demonstrated in heart failure. This study sought to assess myocardial glucose 6-phosphate dehydrogenase activity in retraining of the subpulmonary ventricle of adult goats. ⋯ Both study groups have developed similar right ventricle hypertrophy, regardless less systolic overload exposure of intermittent group. Traditional systolic overload for adult subpulmonary ventricle retraining causes upregulation of myocardial glucose 6-phosphate dehydrogenase activity. It may suggest that the undesirable "pathologic systolic overload" is influenced by activation of penthose pathway and cytosolic Nicotinamide adenine dinucleotide phosphate availability. This altered energy substrate metabolism can elevate levels of free radicals by Nicotinamide adenine dinucleotide phosphate oxidase, an important mechanism in the pathophysiology of heart failure.
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Rev Bras Cir Cardiovasc · Jul 2013
Randomized Controlled TrialEffects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting.
To compare the effects of different levels of positive end-expiratory pressure on respiratory mechanics and oxygenation indexes in the immediate postoperative period of coronary artery bypass grafting. ⋯ Higher levels of positive end-expiratory pressure in immediate postoperative period of coronary artery bypass grafting improved pulmonary compliance values and increased oxygenation indexes, resulting in lower frequency of hypoxemia.
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Rev Bras Cir Cardiovasc · Jun 2013
Acute kidney injury after coronary artery bypass grafting: assessment using RIFLE and AKIN criteria.
To compare the RIFLE (Risk, Injury, Failure, Loss and End-stage Renal Failure) and AKIN (Acute Kidney Injury Network) criteria for diagnosis of acute kidney injury after coronary artery bypass grafting. ⋯ This study showed that the RIFLE and AKIN criteria have a good agreement in the detection and stratification of acute kidney injury after coronary artery bypass grafting.
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Rev Bras Cir Cardiovasc · Dec 2012
Review Meta AnalysisOff-pump versus on-pump coronary artery bypass surgery: meta-analysis and meta-regression of 13,524 patients from randomized trials.
Most recent published meta-analysis of randomized controlled trials (RCTs) showed that off-pump coronary artery bypass graft surgery (CABG) reduces incidence of stroke by 30% compared with on-pump CABG, but showed no difference in other outcomes. New RCTs were published, indicating need of new meta-analysis to investigate pooled results adding these further studies. ⋯ Off-pump CABG reduces the incidence of post-operative stroke by 20.7% and has no substantial effect on mortality or myocardial infarction in comparison to on-pump CABG. Patient gender, number of grafts performed and age do not seem to explain the effect of off-pump CABG on mortality, myocardial infarction or stroke, respectively.
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Rev Bras Cir Cardiovasc · Jul 2012
ReviewNoninvasive mechanical ventilation in the postoperative cardiac surgery period: update of the literature.
This study aimed to update knowledge regarding to noninvasive ventilation (NVI) on postoperative of cardiac surgery in addition at investigating if exists superiority of any modalities NVI in relation to the others. The literature review was performed on the period between 2006 and 2011, on PubMed, SciELO and Lilacs databases crossing the keywords: artificial respiration, continuous positive airway pressure, intermittent positive-pressure ventilation, cardiac surgery and their corresponding in English. ⋯ The NVI modalities that were described on the literature had showed satisfactory results. A few studies compare different NVI modalities; however some of them showed superiority in relation to the others, such as the intermittent positive-pressure ventilation to threat hypoxemia and to positive pressure with bilevel pressure to increase oxygenation, respiratory rate and heart rate in these patients, when compared with other modalities.