Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Apr 2005
Comparative StudyMyocardial blood flow in patients with dilated cardiomyopathy: quantitative assessment with velocity-encoded cine magnetic resonance imaging of the coronary sinus.
To quantify global myocardial perfusion using magnetic resonance imaging (MRI) in patients with heart failure due to idiopathic dilated cardiomyopathy (IDC) and to compare myocardial perfusion and microvascular reactivity with healthy subjects. ⋯ MBF reserve is reduced in patients with IDC, indicating that coronary microcirculatory flow is impaired. This integrated MRI approach allows quantitative measurement of global MBF in humans and may have the potential to study the effects of pharmacological interventions on myocardial perfusion.
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J Magn Reson Imaging · Apr 2005
Magnetic resonance image-guided trans-septal puncture in a swine heart.
To test the feasibility of performing magnetic resonance (MR)-guided trans-septal punctures in the swine heart. ⋯ Using only MR guidance and a novel active intravascular needle system, we were able to repeatedly puncture the fossa ovalis in a swine heart from a transfemoral approach, with direct visualization of all components, including the needle, the atria, the fossa ovalis, and the surrounding vasculature.
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J Magn Reson Imaging · Apr 2005
Reproducibility and dependence on diffusion weighting of line scan diffusion in the lumbar intervertebral discs.
To investigate the dependence of line scan diffusion imaging (LSDI) in the lumbar vertebral discs on diffusion weighting, fat suppression (FS), and postprocessing noise correction. ⋯ LSDI gives reproducible ADC measurements in the lumbar discs, largely independent of b-value and signal-to-noise ratio (SNR) when used with noise correction and FS.
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J Magn Reson Imaging · Apr 2005
Adding another spectral dimension to 1H magnetic resonance spectroscopy of hepatic encephalopathy.
To evaluate a localized two-dimensional correlated magnetic resonance spectroscopic (L-COSY) technique in patients with hepatic encephalopathy (HE) and healthy subjects, and to correlate the cerebral metabolite changes with neuropsychological (NP) test scores. ⋯ The study demonstrated the feasibility of evaluating the two-dimensional L-COSY sequence in a clinical environment. The results showed additional cerebral metabolites that can be measured with the technique in comparison to one-dimensional study.
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J Magn Reson Imaging · Apr 2005
Comparative StudyStandardized assessment of whole body adipose tissue topography by MRI.
To assess standardized whole body adipose tissue topography in a cohort of subjects at an increased risk for type 2 diabetes and to compare fat distribution in subgroups regarding anthropometric (age, body mass index [BMI]) and metabolic parameters (insulin sensitivity). ⋯ Standardized assessment of whole body AT profiles based on T1-weighted MRI provides a reliable basis for interindividual comparison of the body fat distribution and allows a fast and reliable quantification of total body adipose tissue and the distribution of different AT components as subcutaneous and visceral fat in different body regions. Differences in standardized profiles might enable an early identification of people at risk of metabolic disorders, as not only the amount but also the distribution of AT is expected to play an essential role in the pathogenesis of metabolic diseases.