Journal of magnetic resonance imaging : JMRI
-
J Magn Reson Imaging · Apr 2005
Comparative StudyDynamic Gd-DTPA enhanced MRI as a surrogate marker of angiogenesis in tissue-engineered bladder constructs: a feasibility study in rabbits.
To evaluate the potential of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to assess angiogenesis in tissue-engineered bladder constructs in a blinded animal study, and compare different analysis approaches and their correlation with microvessel density (MVD). ⋯ Findings support DCE-MRI for evaluating angiogenesis in bladder constructs and suggest vessel changes other than density. Future studies should incorporate larger contrast agents and permeability assessment to devise an optimal DCE-MRI strategy.
-
J Magn Reson Imaging · Apr 2005
Parallel acquisition techniques for accelerated volumetric interpolated breath-hold examination magnetic resonance imaging of the upper abdomen: assessment of image quality and lesion conspicuity.
To evaluate the impact of parallel acquisition techniques (PATs) on image quality and detection of liver metastases using three-dimensional volumetric interpolated breath-hold examination (VIBE) for clinical liver imaging. ⋯ At least for arrays with small numbers of elements, such as arrays used in this study, the PAT-induced reduction in scanning times must be weighed against compromises in image quality, which translate into poorer diagnostic performance regarding detection of small hepatic lesions. Thus, the PAT implementations tested in this study should probably be reserved for patients unable to hold their breaths for regular three-dimensional VIBE data sets.