Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Apr 2008
Numerical and experimental study of a novel phase contrast magnetic resonance (PC-MR) imaging technique: sparse interleaved referencing PC-MR imaging.
To use numerical simulation and experimental approaches to introduce a novel phase contrast magnetic resonance (PC-MR) data processing technique termed Sparse Interleaved Referencing PC-MR, with potential to improve accuracy, temporal resolution, and signal-to-noise ratio (SNR) of PC-MR data. ⋯ Simulation and in vitro/in vivo results show that Sparse Interleaved Referencing PC-MR processed data in pulsatile and jet flow showed higher accuracy, better peak velocity representation, and improved SNR compared with the data processed using the conventional PC-MR method.
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J Magn Reson Imaging · Apr 2008
Hyperpolarized 129 Xe MRI of the mouse lung at a low xenon concentration using a continuous flow-type hyperpolarizing system.
To apply a continuous flow-type hyperpolarizing (CF-HP) system to lung imaging and investigate the feasibility of hyperpolarized (129)Xe MRI at a low xenon concentration. ⋯ The CF-HP system is useful for lung imaging at an extremely low concentration of xenon, which enables one to fully restrain an anesthetic effect of xenon and to reduce consumption of xenon in a measurement.
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J Magn Reson Imaging · Apr 2008
Comparative StudyComparison between 2D and 3D high-resolution black-blood techniques for carotid artery wall imaging in clinically significant atherosclerosis.
To compare two- (2D) and three-dimensional (3D) black-blood imaging methods for morphological measurements of the carotid artery wall and atherosclerotic plaque. ⋯ 2D and 3D protocols provided comparable morphometric measurements of the carotid artery. The major advantage of 3D imaging is improved small plaque component visualization, while the 2D technique provides higher reliability for image quality.
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J Magn Reson Imaging · Apr 2008
Two-dimensional 1H MR spectroscopy of the brain in human immunodeficiency virus (HIV)-infected children.
To measure cerebral metabolites in brains of human immunodeficiency virus (HIV)-infected patients using two-dimensional (2D) proton ((1)H) magnetic resonance spectroscopy (MRS), which enables more sensitive detection of metabolites at lower concentrations and delineation of the components of the different choline (Ch) groups in the frequency domain when compared to one dimensional (1D) (1)H-MRS. ⋯ We have demonstrated for the first time the feasibility of 2D-MRS in HIV-infected children and adolescents to assess cerebral metabolites and found elevated mI and elevated GABA, in the left frontal brain of clinically stable HIV-infected patients. A larger study population is needed to confirm these pilot GABA findings.
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J Magn Reson Imaging · Apr 2008
Hyperpolarized 3He apparent diffusion coefficient MRI of the lung: reproducibility and volume dependency in healthy volunteers and patients with emphysema.
To measure the apparent diffusion coefficient (ADC) of hyperpolarized (HP) (3)He gas using diffusion weighted MRI in healthy volunteers and patients with emphysema and examine the reproducibility and volume dependency. ⋯ Mean ADC and SD of HP (3)He MRI is reproducible and discriminates well between healthy controls and patients with emphysema at the higher gas volume. This method is robust and may be useful to gain new insights into the pathophysiology and course of emphysema.