Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Feb 2009
Comparative StudyAdded value of breathhold diffusion-weighted MRI in detection of small hepatocellular carcinoma lesions compared with dynamic contrast-enhanced MRI alone using receiver operating characteristic curve analysis.
To evaluate the added value of single-breathhold diffusion-weighted MRI (DWI) in detection of small hepatocellular carcinoma (HCC) lesions (< or =2 cm) in patients with chronic liver disease, by comparing the detection sensitivity of combined DWI/conventional dynamic contrast-enhanced (DCE)-MRI to that of conventional DCE-MRI alone. ⋯ Combined use of breathhold DWI with conventional DCE-MRI helped to provide higher sensitivities than conventional DCE-MRI alone in the detection of small HCC lesions in patients with chronic liver disease.
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J Magn Reson Imaging · Feb 2009
Evaluation of measurement uncertainties in human diffusion tensor imaging (DTI)-derived parameters and optimization of clinical DTI protocols with a wild bootstrap analysis.
To quantify measurement uncertainties of fractional anisotropy, mean diffusivity, and principal eigenvector orientations in human diffusion tensor imaging (DTI) data acquired with common clinical protocols using a wild bootstrap analysis, and to establish optimal scan protocols for clinical DTI acquisitions. ⋯ Our results demonstrate that within a clinically feasible DTI scan time of about 10 minutes, a protocol with number of diffusion gradient directions close to 30 provides nearly optimal measurement results when combined with a ratio of the total number of DW images over non-DW images equal to six. Wild bootstrap can serve as a useful tool to quantify the measurement uncertainty from human DTI data.
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J Magn Reson Imaging · Feb 2009
Prediction of locally recurrent prostate cancer after radiation therapy: incremental value of 3T diffusion-weighted MRI.
To prospectively evaluate the incremental value of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) maps in addition to T2-weighted imaging (T2WI) for predicting locally recurrent prostate cancer in patients with biochemical failure after radiation therapy. ⋯ For predicting locally recurrent prostate cancer after radiation therapy, the use of combined T2WI and DWI showed a better diagnostic performance compared to T2WI.
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J Magn Reson Imaging · Feb 2009
Differentiation of well-differentiated hepatocellular carcinomas from other hepatocellular nodules in cirrhotic liver: value of SPIO-enhanced MR imaging at 3.0 Tesla.
To determine the diagnostic value of superparamagnetic iron oxide (SPIO)-enhanced MRI for the differentiation of well-differentiated hepatocellular carcinomas (WD-HCCs) from other hepatocellular nodules in cirrhotic liver. ⋯ WD-HCCs have characteristic enhancement features that differentiate them from DNs and MD-/PD HCCs on SPIO-enhanced 3.0T MRI. The lesion conspicuity was better on T2*-weighted images than that on T2-weighted images.Inc.
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J Magn Reson Imaging · Feb 2009
Comparative StudyImproved fat suppression using multipeak reconstruction for IDEAL chemical shift fat-water separation: application with fast spin echo imaging.
To evaluate and quantify improvements in the quality of fat suppression for fast spin-echo imaging of the knee using multipeak fat spectral modeling and IDEAL fat-water separation. ⋯ Multipeak IDEAL fat-water separation provides improved fat suppression for T(1)-weighted and T(2)-weighted fast spin-echo imaging of the knee when compared to single-peak IDEAL and two widely used frequency-selected fat-saturation methods.