Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Mar 2010
Comparative StudySmoothing that does not blur: effects of the anisotropic approach for evaluating diffusion tensor imaging data in the clinic.
To compare the effects of anisotropic and Gaussian smoothing on the outcomes of diffusion tensor imaging (DTI) voxel-based (VB) analyses in the clinic, in terms of signal-to-noise ratio (SNR) enhancement and directional information and boundary structures preservation. ⋯ Our study suggests that anisotropic smoothing is more suitable in DTI studies; however, regardless of technique, a moderate level of smoothing seems to be preferable considering the artifacts introduced by this manipulation.
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J Magn Reson Imaging · Mar 2010
Assessment of tumor blood flow in breast tumors with T1-dynamic contrast-enhanced MR imaging: impact of dose reduction and the use of a prebolus technique on diagnostic efficacy.
To prospectively evaluate whether dose reduction and the application of a prebolus technique can effectively alleviate signal saturation effects in T1 dynamic contrast enhanced (T1-DCE) magnetic resonance imaging (MRI) data in breast tumors and lead to increased diagnostic efficacy of the regional tumor blood flow (TBF) values obtained with deconvolution of T1-DCE MRI data. ⋯ Using a prebolus approach provides an estimate of the unsaturated AIF, while reduction of the high-dose bolus minimizes possible saturation effects in the tumor time course.
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J Magn Reson Imaging · Mar 2010
Clinical TrialDelayed gadolinium-enhanced MRI of cartilage in the ankle at 3 T: feasibility and preliminary results after matrix-associated autologous chondrocyte implantation.
To demonstrate the feasibility of delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) in the ankle at 3 T and to obtain preliminary data on matrix associated autologous chondrocyte (MACI) repair tissue. ⋯ It is feasible to assess the thin cartilage layers of the ankle with dGEMRIC at 3 T; MACI can yield RT with properties similar to articular cartilage.
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J Magn Reson Imaging · Mar 2010
Case ReportsWhole-body MR imaging for the evaluation of McCune-albright syndrome.
This paper is a detailed case study of a seven-year-old girl who developed precocious puberty. The young girl experienced bilateral breast enlargement, vaginal discharge, and multiple areas of "cafe-au-lait" pigmentation on the skin. The skeletal radiographs showed multiple bone lesions which were suggestive of polyostotic fibrous dysplasia. ⋯ The MRI showed approximately the same number of osseous lesions compared to the skeletal radiographs. In addition, the MRI detected a cystic lesion localized in the pelvis that raised the possibility of an ovarian-follicular cyst. This case suggests that whole-body MRI might be a promising method for the evaluation and follow-up of polyostotic fibrous dysplasia, a disease with diffuse involvement of the musculoskeletal system.
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J Magn Reson Imaging · Mar 2010
Prostate cancer detection with 3 T MRI: comparison of diffusion-weighted imaging and dynamic contrast-enhanced MRI in combination with T2-weighted imaging.
To evaluate the diagnostic ability of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCEI) in combination with T2-weighted imaging (T2WI) for the detection of prostate cancer using 3 T magnetic resonance imaging (MRI) with a phased-array body coil. ⋯ In patients with elevated PSA levels the combination of T2WI, DWI, DCEI using 3 T MRI may be a reasonable approach for the detection of prostate cancer.