Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Mar 2010
Comparative StudyMachine learning study of several classifiers trained with texture analysis features to differentiate benign from malignant soft-tissue tumors in T1-MRI images.
To study, from a machine learning perspective, the performance of several machine learning classifiers that use texture analysis features extracted from soft-tissue tumors in nonenhanced T1-MRI images to discriminate between malignant and benign tumors. ⋯ Machine learning classifiers trained with texture analysis features are potentially valuable for detecting malignant tumors in T1-MRI images. Analysis of the learning curves of the classifiers showed that a training data size smaller than 100 T1-MRI images is sufficient to train a machine learning classifier that performs as well as expert radiologists.
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J Magn Reson Imaging · Mar 2010
Comparative StudyComparison of ferucarbotran-enhanced fluid-attenuated inversion-recovery echo-planar, T2-weighted turbo spin-echo, T2*-weighted gradient-echo, and diffusion-weighted echo-planar imaging for detection of malignant liver lesions.
To compare the diagnostic accuracy of superparamagnetic iron oxide (SPIO)-enhanced fluid-attenuated inversion-recovery echo-planar imaging (FLAIR EPI) for malignant liver tumors with that of T2-weighted turbo spin-echo (TSE), T2*-weighted gradient-echo (GRE), and diffusion-weighted echo-planar imaging (DW EPI). ⋯ SPIO-enhanced FLAIR EPI sequence was more accurate in the diagnosis of malignant liver tumors than T2*-weighted GRE and DW EPI sequences. SPIO-enhanced FLAIR EPI sequence is helpful for the detection of malignant liver tumors.
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J Magn Reson Imaging · Mar 2010
Assessment of tumor blood flow in breast tumors with T1-dynamic contrast-enhanced MR imaging: impact of dose reduction and the use of a prebolus technique on diagnostic efficacy.
To prospectively evaluate whether dose reduction and the application of a prebolus technique can effectively alleviate signal saturation effects in T1 dynamic contrast enhanced (T1-DCE) magnetic resonance imaging (MRI) data in breast tumors and lead to increased diagnostic efficacy of the regional tumor blood flow (TBF) values obtained with deconvolution of T1-DCE MRI data. ⋯ Using a prebolus approach provides an estimate of the unsaturated AIF, while reduction of the high-dose bolus minimizes possible saturation effects in the tumor time course.
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J Magn Reson Imaging · Mar 2010
Clinical TrialDelayed gadolinium-enhanced MRI of cartilage in the ankle at 3 T: feasibility and preliminary results after matrix-associated autologous chondrocyte implantation.
To demonstrate the feasibility of delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) in the ankle at 3 T and to obtain preliminary data on matrix associated autologous chondrocyte (MACI) repair tissue. ⋯ It is feasible to assess the thin cartilage layers of the ankle with dGEMRIC at 3 T; MACI can yield RT with properties similar to articular cartilage.
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J Magn Reson Imaging · Mar 2010
Case ReportsWhole-body MR imaging for the evaluation of McCune-albright syndrome.
This paper is a detailed case study of a seven-year-old girl who developed precocious puberty. The young girl experienced bilateral breast enlargement, vaginal discharge, and multiple areas of "cafe-au-lait" pigmentation on the skin. The skeletal radiographs showed multiple bone lesions which were suggestive of polyostotic fibrous dysplasia. ⋯ The MRI showed approximately the same number of osseous lesions compared to the skeletal radiographs. In addition, the MRI detected a cystic lesion localized in the pelvis that raised the possibility of an ovarian-follicular cyst. This case suggests that whole-body MRI might be a promising method for the evaluation and follow-up of polyostotic fibrous dysplasia, a disease with diffuse involvement of the musculoskeletal system.