Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Sep 2013
Subcompartmentalization of extracellular extravascular space (EES) into permeability and leaky space with local arterial input function (AIF) results in improved discrimination between high- and low-grade glioma using dynamic contrast-enhanced (DCE) MRI.
To modify the generalized tracer kinetic model (GTKM) by introducing an additional tissue uptake leakage compartment in extracellular extravascular space (LTKM). In addition, an implicit determination of voxel-wise local arterial input function (AIF) Cp (t) was performed to see whether these changes help in better discrimination between low- and high-grade glioma using dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). ⋯ LTKM with local AIF provides more accurate estimation of physiological parameters and improves discrimination between low-grade and high-grade gliomas as compared with GTKM.
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J Magn Reson Imaging · Sep 2013
Diffusion tensor imaging of normal-appearing white matter in unilateral cerebral arterial occlusive disease.
To use MR with diffusion tensor imaging (DTI) and conventional and high b value to assess diffusion changes in normal-appearing white matter (NAWM) in patients with unilateral, severe stenosis, or occlusion of the middle cerebral artery (MCA). ⋯ DTI with a high b value detects diffusion changes in NAWM in patients with unilateral, severe stenosis, or occlusion of the MCA not seen with conventional b value or conventional MRI contrasts.