Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · May 2017
Longitudinal study using voxel-based relaxometry: Association between cartilage T1ρ and T2 and patient reported outcome changes in hip osteoarthritis.
To study the local distribution of hip cartilage T1ρ and T2 relaxation times and their association with changes in patient reported outcome measures (PROMs) using a fully automatic, local, and unbiased method in subjects with and without hip osteoarthritis (OA). ⋯ 1 J. MAGN. RESON. IMAGING 2017;45:1523-1533.
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J Magn Reson Imaging · May 2017
Diffusion kurtosis imaging for differentiating between the benign and malignant sinonasal lesions.
The study aimed to evaluate diffusion kurtosis imaging (DKI) in the differentiation between benign and malignant sinonasal lesions, and to compare the diagnostic performance of DKI with diffusion weighted imaging (DWI). ⋯ 1 J. MAGN. RESON. IMAGING 2017;45:1446-1454.
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J Magn Reson Imaging · May 2017
ReviewLiver fibrosis: Review of current imaging and MRI quantification techniques.
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis and cirrhosis. The severity of liver fibrosis influences the decision to treat or the need to monitor hepatic or extrahepatic complications. ⋯ Further, some techniques are only available on MRI-such as spin-lattice relaxation time in the rotating frame (T1 ρ), diffusion of water molecules, and hepatocellular function based on the uptake of a liver-specific contrast agent-remain investigational in the setting of liver fibrosis staging. In this review, we summarize the key concepts, advantages and limitations, and diagnostic performance of each technique. The use of multiparametric MRI techniques offers the potential for comprehensive assessment of chronic liver disease severity.
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J Magn Reson Imaging · May 2017
Brain white matter changes in CPAP-treated obstructive sleep apnea patients with residual sleepiness.
To investigate white matter (WM) structural alterations using diffusion tensor imaging (DTI) in obstructive sleep apnea (OSA) patients, with or without residual sleepiness, following adherent continuous positive airway pressure (CPAP) treatment. Possible quantitative relationships were explored between the DTI metrics and two clinical assessments of somnolence. ⋯ Global and regional WM alterations, as revealed by DTI, can be a possible mechanism to explain why OSA patients with high levels of CPAP use can have differing responses to treatment. Compromised myelin sheath, indicated by increased radial diffusivity, can be involved in the underlying WM changes. Evidence level: 1 J. MAGN. RESON. IMAGING 2017;45:1371-1378.