Journal of magnetic resonance imaging : JMRI
-
J Magn Reson Imaging · Nov 2012
Quantitative mapping of total choline in healthy human breast using proton echo planar spectroscopic imaging (PEPSI) at 3 Tesla.
To quantitatively measure tCho levels in healthy breasts using Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI). ⋯ The detection sensitivity of PEPSI is comparable to SVS and conventional PRESS-MRSI. PEPSI can be potentially used in the evaluation of tCho in breast cancer. A tCho threshold concentration value of ∼0.7 mmol/kg might be used to differentiate between cancerous and healthy (or benign) breast tissues based on this work and previous studies.
-
J Magn Reson Imaging · Nov 2012
Flow-sensitive 4D MRI of the thoracic aorta: comparison of image quality, quantitative flow, and wall parameters at 1.5 T and 3 T.
To evaluate the effect of field strength on flow-sensitive 4D magnetic resonance imaging (MRI) of the thoracic aorta. A volunteer study at 1.5 T and 3 T was conducted to compare phase-contrast MR angiography (MRA) and 3D flow visualization quality as well as quantification of aortic hemodynamics. ⋯ Flow-sensitive 4D MRI at 3 T provided improved image quality without additional artifacts related to higher fields. Imaging at 1.5 T MRI, which is more widely available, was also feasible and provided information on aortic 3D hemodynamics of moderate quality with identical performance regarding quantitative analysis.
-
The technology of musculoskeletal magnetic resonance imaging (MRI) is advancing at a dramatic rate. MRI is now done at medium and higher field strengths with more specialized surface coils and with more variable pulse sequences and postprocessing techniques than ever before. ⋯ Substantial technical advances have considerable clinical challenges in musculoskeletal radiology such as postoperative patient imaging, cartilage mapping, and molecular imaging. In this review we consider technical advances in hardware and software of musculoskeletal MRI along with their clinical applications.
-
J Magn Reson Imaging · Oct 2012
Diffusion tensor imaging (DTI) with retrospective motion correction for large-scale pediatric imaging.
To develop and implement a clinical DTI technique suitable for the pediatric setting that retrospectively corrects for large motion without the need for rescanning and/or reacquisition strategies, and to deliver high-quality DTI images (both in the presence and absence of large motion) using procedures that reduce image noise and artifacts. ⋯ This work suggests that, apart from the rare instance of continuous motion throughout the scan, high-quality DTI brain data can be acquired using our proposed integrated sequence and reconstruction that uses a retrospective approach to motion correction. In addition, we demonstrate a substantial improvement in overall image quality by combining phase correction with complex averaging, which reduces the Rician noise that biases noisy data.
-
To implement a method using an extended phase graph (EPG)-based simulation to optimize inversion-prepared gradient echo sequences with respect to signal and contrast within the shortest acquisition time. ⋯ From the experiment results, it is demonstrated that optimization of 3D magnetization-prepared rapid gradient-echo imaging sequences can be performed with an EPG-based simulation to manipulate the sequence parameters for generating images with highly specific signal and contrast characteristics for quantitative T1-weighted human brain imaging.