Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Sep 2012
Comparative StudyWhich is the best MRI marker of malignancy for atypical cirrhotic nodules: hypointensity in hepatobiliary phase alone or combined with other features? Classification after Gd-EOB-DTPA administration.
To investigate whether the malignancy of atypical nodules in cirrhosis can be identified at gadoxetic-acid-disodium(Gd-EOB-DTPA)-MRI by their hypointensity in the hepatobiliary(HB)-phase alone or combined with any other MR imaging features. ⋯ In atypical cirrhotic nodules, HB-phase hypointensity by itself is the strongest marker of malignancy.
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To implement a method using an extended phase graph (EPG)-based simulation to optimize inversion-prepared gradient echo sequences with respect to signal and contrast within the shortest acquisition time. ⋯ From the experiment results, it is demonstrated that optimization of 3D magnetization-prepared rapid gradient-echo imaging sequences can be performed with an EPG-based simulation to manipulate the sequence parameters for generating images with highly specific signal and contrast characteristics for quantitative T1-weighted human brain imaging.
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J Magn Reson Imaging · Sep 2012
Discrimination of axillary metastatic from nonmetastatic lymph nodes with PROPELLER diffusion-weighted MR imaging in a metastatic breast cancer model and its correlation with cellularity.
To assess the accuracy of apparent diffusion coefficient (ADC) in the differentiation of axillary metastatic from nonmetastatic lymph nodes in rabbits with metastatic breast cancer and to determine the relationship between the ADC and the cellularity of axillary lymph nodes of two different types. ⋯ DW imaging is a new promising functional technique for differentiating metastatic from inflammatory lymph nodes. Furthermore, cellularity has a significant influence on the ADC in both malignant and benign lymph nodes.
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J Magn Reson Imaging · Aug 2012
Test-retest stability analysis of resting brain activity revealed by blood oxygen level-dependent functional MRI.
To assess test-retest stability of four functional magnetic resonance imaging (fMRI)-derived resting brain activity metrics: the seed-region-based functional connectivity (SRFC), independent component analysis (ICA)-derived network-based FC (NTFC), regional homogeneity (ReHo), and the amplitude of low frequency fluctuation (ALFF). ⋯ SRFC, ReHo, and ALFF are robust to random noise interference. The neighborhood size for calculating ReHo should be larger than 20 voxels. ICC > 0.5 and cluster size > 11 should be used to assess the ICC maps for ACC/PCC SRFC, ReHo, and ALFF. BOLD fMRI-based SBA can be reliably measured using ACC/PCC SRFC, ReHo, and ALFF after 2 months.
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J Magn Reson Imaging · Aug 2012
Development and evaluation of TWIST Dixon for dynamic contrast-enhanced (DCE) MRI with improved acquisition efficiency and fat suppression.
To develop a new pulse sequence called time-resolved angiography with stochastic trajectories (TWIST) Dixon for dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). ⋯ The results from phantom and volunteer evaluation suggest that TWIST Dixon outperforms conventional methods in almost every aspect and it is a promising method for DCE-MRI and contrast-enhanced perfusion MRI, especially at higher field strength where fat suppression is challenging.