Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Aug 2010
Effects of gradient non-linearity correction and intensity non-uniformity correction in longitudinal studies using structural image evaluation using normalization of atrophy (SIENA).
To evaluate the effects of gradient nonlinearity correction and intensity nonuniformity correction on longitudinal (two-year) changes in global and regional brain volumes. ⋯ Correction for gradient nonlinearity and intensity nonuniformity reduces the variance of measured longitudinal changes in brain volumes and will improve accuracy for detecting subtle brain changes.
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J Magn Reson Imaging · Aug 2010
Impact of motion on T1 mapping acquired with inversion recovery fast spin echo and rapid spoiled gradient recalled-echo pulse sequences for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in volunteers.
To evaluate the impact of motion on T1 values acquired by using either inversion-recovery fast spin echo (IR-FSE) or three-dimensional (3D) spoiled gradient recalled-echo (SPGR) sequences for delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) in volunteers. ⋯ Involuntary motion has a significant influence on T1 values acquired with IR-FSE, but not with 3D-SPGR in healthy volunteers.
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J Magn Reson Imaging · Jul 2010
Comparative StudyDiffusion tensor imaging of the pediatric optic nerve: intrinsic and extrinsic pathology compared to normal controls.
To establish normative magnetic resonance diffusion tensor imaging (MRDTI) data in the pediatric optic nerve and compare to pathologic conditions both intrinsic and extrinsic to the anterior optic nerve pathway. ⋯ MRDTI is a feasible technique for evaluating the optic nerves in pediatric patients. It may play a role in presurgical planning by demonstrating integrity of the visual pathway in patients with resectable lesions, allowing for minimization of morbidity associated with vision loss.
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J Magn Reson Imaging · Jul 2010
Comparative StudyComparison of dual to single contrast bolus magnetic resonance myocardial perfusion imaging for detection of significant coronary artery disease.
To investigate the incremental diagnostic value of dual-bolus over single-contrast-bolus first pass magnetic resonance myocardial perfusion imaging (MR-MPI) for detection of significant coronary artery disease (CAD). ⋯ In this study the dual-bolus technique had no incremental diagnostic value over single-bolus technique for detection of significant CAD with the used contrast concentrations.
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J Magn Reson Imaging · Jul 2010
Reproducibility of in vivo magnetic resonance imaging-based measurement of myelin water.
To evaluate the reproducibility of multicomponent quantitative T(2) (QT2) measurements, in particular the myelin water fraction (MWF), to determine the sensitivity of this method for monitoring myelin changes in longitudinal studies and to provide a basis for correctly powering such studies. ⋯ The reproducibility of QT2 measurements using existing methods is moderate and the method can be used in longitudinal studies, with careful consideration of the methodologic variability and an appropriate group size.