Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Dec 2009
Gadolinium-based contrast agents and nephrogenic systemic fibrosis: why did it happen and what have we learned?
This article addresses two questions about gadolinium-based contrast agents (GBCAs) and nephrogenic systemic fibrosis (NSF): "Why did it happen" and "What have we learned"? It reviews the events leading to the discovery of an association between NSF and GBCAs. Various factors are elucidated that contributed to the delay between the time when GBCA came into widespread clinical use and a link was made with NSF, including use in renal-compromised patients, high-dose magnetic resonance angiography (MRA), lack of documentation and adequate databases, policy and regulatory changes, and an absence of scientific evidence. The authors conclude that the overriding cause was lack of awareness. ⋯ Magn. Reson. Imaging 2009;30:1236-1239. (c) 2009 Wiley-Liss, Inc.
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J Magn Reson Imaging · Nov 2009
Comparative StudyComparison of methods to assess quadriceps muscle volume using magnetic resonance imaging.
To compare the precision of four methods to estimate the volume of quadriceps muscles using axial MRI. ⋯ While methods based on interpolation and deformation of a parametric specific object have not been used in literature, these two methods are the most precise approaches to reach a given level of precision.
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J Magn Reson Imaging · Nov 2009
Diffusion-weighted imaging of human carotid artery using 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (2D ss-IMIV-DWEPI) at 3T: diffusion measurement in atherosclerotic plaque.
To determine if 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (ss-IMIV-DWEPI) can be used to obtain quantitative diffusion measurements that can assist in the identification of plaque components in the cervical carotid artery. ⋯ 2D ss-IMIV-DWEPI can perform diffusion-weighted carotid magnetic resonance imaging (MRI) in vivo with reasonably high spatial resolution (1 x 1 x 2 mm(3)). ADC values of the carotid wall and plaque are consistent with similar values obtained from ex vivo endarterectomy specimens. The spread in ADC values obtained from plaque indicate that this technique could form a basis for plaque component identification in conjunction with other MRI/MRA techniques.