Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Oct 2008
Manganese-enhanced MRI of the rat visual pathway: acute neural toxicity, contrast enhancement, axon resolution, axonal transport, and clearance of Mn(2+).
To provide dose-response data for the safe and effective use of MnCl(2) for manganese (Mn(2+)) -enhanced MRI (MEMRI) of the visual pathway. ⋯ The optimal dose for MEMRI of the rat visual pathway was found to be 150-300 nmol ivit MnCl(2). Higher doses are toxic, causing RGC death, impair active clearance from the vitreous, and loss of Mn(2+) enhancement throughout the visual pathway. Mn(2+) traffic within RGC axons is mediated mainly by anterograde transport.
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In 1984, Dixon published a first paper on a simple spectroscopic imaging technique for water and fat separation. The technique acquires two separate images with a modified spin echo pulse sequence. One is a conventional spin echo image with water and fat signals in-phase and the other is acquired with the readout gradient slightly shifted so that the water and fat signals are 180 degrees out-of-phase. ⋯ These applications, as well as the potential that the technique can be made highly insensitive to magnetic field inhomogeneity, have generated substantial research interests and efforts from many investigators. As a result, significant improvement to the original technique has been made in the last 2 decades. The following article reviews the underlying physical principles and describes some major technical aspects in the development of these Dixon techniques.
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J Magn Reson Imaging · Sep 2008
Multicenter StudyEvaluation of cardiac biventricular segmentation from multiaxis MRI data: a multicenter study.
To validate a volumetric biventricular segmentation solution for multiaxis cardiac magnetic resonance (CMR) images. ⋯ Fully automatic segmentation produces good results in the assessment of left ventricular volume andendocardial border. Two minutes of user interaction are needed to obtain accurate results for the right ventricle.
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J Magn Reson Imaging · Sep 2008
Feasibility of diffusion-weighted imaging in the differentiation of metastatic from nonmetastatic lymph nodes: early experience.
To investigate the feasibility of diffusion-weighted imaging (DWI) in the differentiation of metastatic from nonmetastatic lymph nodes. ⋯ DWI is feasible for differentiating metastatic from nonmetastatic lymph nodes in patients with uterine cervical cancer.