Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Oct 2008
Comparative StudyDiffusion-weighted MR imaging for the evaluation of seminal vesicle invasion in prostate cancer: initial results.
To evaluate the accuracy of T2-weighted (T2WI) with diffusion-weighted imaging (DWI) as compared with T2WI alone for predicting seminal vesicle invasion (SVI) of prostate cancer. ⋯ For predicting SVI, T2WI with DWI showed a better diagnostic performance than T2WI alone. Additionally, the accuracy of the less experienced reader using T2WI with DWI showed a significant improvement as compared with T2WI alone.
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J Magn Reson Imaging · Sep 2008
Comparative StudyFree-breathing, nongated real-time delayed enhancement MRI of myocardial infarcts: a comparison with conventional delayed enhancement.
To compare a free-breathing, nongated, and black-blood real-time delayed enhancement (RT-DE) sequence to the conventional inversion recovery gradient echo (IR-GRE) sequence for delayed enhancement MRI. ⋯ RT-DE can be used for delayed enhancement imaging during free-breathing and without cardiac gating.
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In 1984, Dixon published a first paper on a simple spectroscopic imaging technique for water and fat separation. The technique acquires two separate images with a modified spin echo pulse sequence. One is a conventional spin echo image with water and fat signals in-phase and the other is acquired with the readout gradient slightly shifted so that the water and fat signals are 180 degrees out-of-phase. ⋯ These applications, as well as the potential that the technique can be made highly insensitive to magnetic field inhomogeneity, have generated substantial research interests and efforts from many investigators. As a result, significant improvement to the original technique has been made in the last 2 decades. The following article reviews the underlying physical principles and describes some major technical aspects in the development of these Dixon techniques.
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J Magn Reson Imaging · Sep 2008
Dynamic contrast-enhanced (DCE) derived transfer coefficient (ktrans) is a surrogate marker of matrix metalloproteinase 9 (MMP-9) expression in brain tuberculomas.
To correlate dynamic contrast-enhanced (DCE) MRI derived perfusion indices with immunohistochemically obtained vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) in a cellular fraction of brain tuberculomas (BT). ⋯ We conclude that the expression of MMP-9, a marker of BBB disruption and disease activity in BT correlates with DCE-derived ktrans and thus has the potential to be used as its surrogate marker.