Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Apr 2005
Randomized Controlled Trial Comparative Study Clinical TrialContrast-enhanced magnetic resonance angiography of the lower extremities: standard-dose vs. high-dose gadodiamide injection.
To compare the efficacy and safety of two different doses (0.1 and 0.3 mmol/kg of body weight [BW]) of gadodiamide for contrast-enhanced magnetic resonance angiography (ce-MRA) of the lower extremities with intraarterial digital subtraction angiography (IA-DSA). ⋯ Ce-MRA with gadodiamide is safe and efficacious. Comparison of two different doses with IA-DSA as the standard of reference showed that the 0.3 mmol/kg dose is superior to the standard 0.1 mmol/kg dose with respect to contrast enhancement, vessel delineation, image quality, and detection of collaterals. However, the 0.1 mmol/kg dose was superior to the high dose in the grading of stenosis.
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J Magn Reson Imaging · Apr 2005
Randomized Controlled Trial Clinical TrialEffect of ingestion order of the fat component of a solid meal on intragastric fat distribution and gastric emptying assessed by MRI.
To develop an MRI technique to investigate how varying the ingestion order of nonfat and fat components of a solid meal influences three-dimensional intragastric distribution and gastric emptying (GE). ⋯ Meal ingestion order influences GE and intragastric distribution of fat, which can be assessed by MRI techniques, providing new insights into the physiology of gastric processing and intragastric distribution of different meal phases.
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J Magn Reson Imaging · Apr 2005
Comparative StudyHigh-resolution diffusion-weighted imaging with interleaved variable-density spiral acquisitions.
To develop a multishot magnetic resonance imaging (MRI) pulse sequence and reconstruction algorithm for diffusion-weighted imaging (DWI) in the brain with submillimeter in-plane resolution. ⋯ The self-navigated multishot variable-density spiral acquisition provides a time-efficient approach to acquire high-resolution diffusion-weighted images on a clinical scanner. The reconstruction algorithm based on motion correction in the k-space data is robust, and measured ADC values are accurate and reproducible.
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J Magn Reson Imaging · Apr 2005
Comparative StudyMyocardial blood flow in patients with dilated cardiomyopathy: quantitative assessment with velocity-encoded cine magnetic resonance imaging of the coronary sinus.
To quantify global myocardial perfusion using magnetic resonance imaging (MRI) in patients with heart failure due to idiopathic dilated cardiomyopathy (IDC) and to compare myocardial perfusion and microvascular reactivity with healthy subjects. ⋯ MBF reserve is reduced in patients with IDC, indicating that coronary microcirculatory flow is impaired. This integrated MRI approach allows quantitative measurement of global MBF in humans and may have the potential to study the effects of pharmacological interventions on myocardial perfusion.
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J Magn Reson Imaging · Apr 2005
Magnetic resonance image-guided trans-septal puncture in a swine heart.
To test the feasibility of performing magnetic resonance (MR)-guided trans-septal punctures in the swine heart. ⋯ Using only MR guidance and a novel active intravascular needle system, we were able to repeatedly puncture the fossa ovalis in a swine heart from a transfemoral approach, with direct visualization of all components, including the needle, the atria, the fossa ovalis, and the surrounding vasculature.