Journal of magnetic resonance imaging : JMRI
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The purpose of this study was development of an actively visualized .035-inch vascular guidewire for use in MR-guided interventions. The guidewire was actively visualized by inclusion of a 6-cm-long radiofrequency coil in its tip. A high contrast outline of the distal tip of the guidewire was obtained by acquiring an image with the radiofrequency coil as the receiving antenna. ⋯ The guidewire was evaluated in vivo in the abdominal vessels of a rabbit and swine at 1.5 T. The built-in radiofrequency coil delivered a high contrast signal over its full length, enabling visualization of the position and curvature of the tip of the guidewire. The ability to see the curvature of the guidewire over several centimeters significantly eased manipulation into targeted vessels and represents an important advance toward MR-guided vascular interventions.
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J Magn Reson Imaging · Jan 1998
MR monitoring of MR-guided radiofrequency thermal ablation of normal liver in an animal model.
The purpose of this study was to determine the suitability of MRI to accurately detect radiofrequency (RF) thermoablative lesions created under MR guidance. In vivo RF lesions were created in the livers of six New Zealand White rabbits using a 2-mm-diameter titanium alloy RF electrode with a 20-mm exposed tip and a 50-W RF generator. This was performed using a 0.2T clinical C-arm MR imager for guidance and monitoring. ⋯ Lesion dimensions determined from images closely correlated with those determined at gross examination with the discrepancy never exceeding 2 mm, for an r2 value of .87. MRI performed at the time of MR-guided RF ablation accurately demonstrated created lesions. This modality may provide a new option for the treatment of local and regional neoplastic disease.
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J Magn Reson Imaging · Jan 1998
Visualization of MR-compatible catheters by electrically induced local field inhomogeneities: evaluation in vivo.
The purpose of this study was to assess the feasibility of a newly developed field inhomogeneity catheter for interventional MRI in vivo. Different prototypes of a field inhomogeneity catheter (pigtail and multipurpose configuration, balloon catheters) were investigated in pigs. The catheters were introduced in Seldinger technique via the femoral vessels over a guidewire on an interventional MR system (Philips Gyroscan NT combined with a C-arm fluoroscopy unit [Philips BV 212]). ⋯ Although aortic branches were successful cannulated, the catheters were not well displayed by the TFE technique due to the complex and tortuous anatomy. All animals survived the experiments without complications. MR-guided visualization of a field inhomogeneity catheter is a simple concept that can be realized on each MR scanner and may allow intravascular MR-guided interventions in future.
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J Magn Reson Imaging · Jan 1998
Shifted rotated keyhole imaging and active tip-tracking for interventional procedure guidance.
The tools and devices used for patient treatment during interventional procedures must be accurately and safely localized. Recently, procedure guidance has been performed increasingly with MRI, but tool localization has been performed primarily by analyzing the lack of signal caused by displaced excited tissue and/or susceptibility artifacts. ⋯ Unlike earlier methods, in which images from small device-mounted coils are super-imposed on a previously acquired image data set, our localization method uses similar tip-mounted tools in combination with a radiofrequency (RF) switching circuit, standard imaging coils, and specially modified sequences to toggle between the standard and tip-mounted receive coil within a single fluoroscopic mode sequence. With this technique, the misregistration between the reported anatomic location and true location of interventional devices is minimized.
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J Magn Reson Imaging · Jan 1998
Malignant hepatic tumors: changes on MRI after hepatic arterial chemoembolization--preliminary findings.
This study describes the MR appearances of malignant hypervascular liver lesions pre- and post-hepatic-arterial chemoembolization, with correlation to serial imaging and clinical responses. Eight patients with malignant hypervascular liver lesions underwent pretreatment and posttreatment MR examination on a 1.5-T MR imager. MR sequences included T1-weighted spoiled gradient echo (SGE), T2-weighted fat-suppressed spin echo or turbo spin echo, and dynamic gadolinium-enhanced SGE images. ⋯ MR response of lesions that showed poor clinical response demonstrated no change in lesion appearances compared with the pretreatment MR study. Our results demonstrated change in appearance of liver lesions between pre- and post-hepatic-arterial chemoembolization MR studies. MR response correlated with response determined by serial imaging studies and clinical findings.