Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Nov 2017
Progressive iron accumulation across multiple sclerosis phenotypes revealed by sparse classification of deep gray matter.
To create an automated framework for localized analysis of deep gray matter (DGM) iron accumulation and demyelination using sparse classification by combining quantitative susceptibility (QS) and transverse relaxation rate (R2*) maps, for evaluation of DGM in multiple sclerosis (MS) phenotypes relative to healthy controls. ⋯ 1 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2017;46:1464-1473.
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J Magn Reson Imaging · Nov 2017
Diffusion kurtosis imaging for differentiating borderline from malignant epithelial ovarian tumors: A correlation with Ki-67 expression.
To investigate the use of diffusion kurtosis imaging (DKI) in differentiating borderline from malignant epithelial ovarian tumors (MEOTs) and to correlate DKI parameters with Ki-67 expression. ⋯ 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2017;46:1499-1506.
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J Magn Reson Imaging · Nov 2017
Fast bilateral breast coverage with high spectral and spatial resolution (HiSS) MRI at 3T.
To develop and assess a full-coverage, sensitivity encoding (SENSE)-accelerated breast high spatial and spectral resolution (HiSS) magnetic resonance imaging (MRI) within clinically reasonable times as a potential nonenhanced MRI protocol for breast density measurement or breast cancer screening. ⋯ 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2017;46:1341-1348.
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J Magn Reson Imaging · Nov 2017
Feasibility of 3D navigator-triggered magnetic resonance cholangiopancreatography with combined parallel imaging and compressed sensing reconstruction at 3T.
To assess the feasibility of 3D navigator-triggered magnetic resonance cholangiopancreatography (MRCP) with combined parallel imaging (PI) and compressed sensing (CS). ⋯ 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2017;46:1289-1297.
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J Magn Reson Imaging · Oct 2017
ReviewClinical quantitative susceptibility mapping (QSM): Biometal imaging and its emerging roles in patient care.
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI) of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense blooming artifacts to precise quantitative measurement of spatial biodistributions. QSM technology may be regarded to be sufficiently developed and validated to warrant wide dissemination for clinical applications of imaging isotropic susceptibility, which is dominated by metals in tissue, including iron and calcium. These biometals are highly regulated as vital participants in normal cellular biochemistry, and their dysregulations are manifested in a variety of pathologic processes. ⋯ In brief, QSM can be generated with postprocessing whenever gradient echo MRI is performed. QSM can be useful for diseases that involve neurodegeneration, inflammation, hemorrhage, abnormal oxygen consumption, substantial alterations in highly paramagnetic cellular iron, bone mineralization, or pathologic calcification; and for all disorders in which MRI diagnosis or surveillance requires contrast agent injection. Clinicians may consider integrating QSM into their routine imaging practices by including gradient echo sequences in all relevant MRI protocols.