Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Anasthesiol Intensivmed Notfallmed Schmerzther · Aug 1997
Review[Intramucosal pCO2 measurement as gastrointestinal monitoring].
The improvement of tissue perfusion by alterations in global parameters has led to the concept of supranormal oxygen delivery. However, this approach did not cause a significant reduction in the mortality of critical illness. As a consequence, recent research activity concentrates on regional monitoring and on the therapy of especially vulnerable, injury-prone organ systems. ⋯ Therefore, the rather confusing terms "gastric tonometry" and "pHi measurement" should be avoided and the new monitoring technique be defined as "intramucosal pCO2 measurement". Continuous piCO2-measurement is a monitoring technique with high sensitivity in detecting gastrointestinal hypoperfusion based on an intramucosal CO2 accumulation. The clinical significance of the primary parameter piCO2 as well as the suitability of this technique as a monitoring tool for the daily routine must be re-assessed.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Aug 1997
Randomized Controlled Trial Clinical Trial[Differential indications for non-opioids for postoperative analgesia III. Analgesic effect of perioperative administration of metamizole plus diclofenac after spinal anesthesia].
In a previous study we investigated the analgesic efficacy of a combination of metamizol plus diclofenac after general anaesthesia. After minor orthopaedic surgery postoperative opioid requirements were reduced by 73% during the first 24 h after surgery. In the present study, we have investigated the efficacy of this analgesic combination after minor orthopaedic operations performed in spinal anaesthesia. ⋯ The combination of metamizol and diclofenac causes a clinically relevant reduction in opioid requirements after minor orthopaedic surgery in spinal anaesthesia.