Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Oct 2004
Comment Letter Comparative StudyDecreased release of endothelin after OPCAB: implications of the evidence.
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J. Cardiothorac. Vasc. Anesth. · Oct 2004
Cardiopulmonary bypass reduces the minimum alveolar concentration for isoflurane.
The purpose of this investigation was to determine the influence of cardiopulmonary bypass (CPB) on the minimum alveolar concentration (MAC) of isoflurane in a rat model of CPB. ⋯ CPB resulted in a small (10%) but significant reduction in the MAC for isoflurane. The mechanism behind this reduction in MAC is not clear but may be related to CPB-induced cerebral injury.