Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Apr 2004
Randomized Controlled Trial Comparative Study Clinical TrialMilrinone and nitric oxide: combined effect on pulmonary artery pressures after cardiopulmonary bypass in children.
To investigate the effect of milrinone combined with nitric oxide (NO) on the pulmonary artery pressures (PAP) after cardiopulmonary bypass (CPB), for repair of congenital heart defects (CHD) in children. ⋯ The combination of milrinone and NO produced a more pronounced decrease in PAP than milrinone alone.
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J. Cardiothorac. Vasc. Anesth. · Apr 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery.
This study compared the efficacy of aminocaproic acid and tranexamic acid in reducing postoperative blood loss, as well as blood and blood product requirements in children with cyanotic congenital heart disease. ⋯ Aminocaproic acid and tranexamic acid are equally effective in reducing postoperative blood loss, as well as blood and blood product requirements in children with cyanotic heart disease undergoing corrective surgery as compared with the control group.
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J. Cardiothorac. Vasc. Anesth. · Apr 2004
Randomized Controlled Trial Clinical TrialDecreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass.
To determine if preoperative heparin therapy causes an increase in the incidence of intraoperative heparin resistance by reducing the concentration of antithrombin in plasma. ⋯ Preoperative heparin causes an increased incidence of heparin resistance and reduced antithrombin concentrations. However, heparin resistance was not causally related to reduced antithrombin because antithrombin concentrations were not different between heparin-resistant and heparin-responsive patients in the POHI group.
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J. Cardiothorac. Vasc. Anesth. · Apr 2004
Randomized Controlled Trial Comparative Study Clinical TrialEffectiveness of a circulating-water warming garment in rewarming after pediatric cardiac surgery using hypothermic cardiopulmonary bypass.
To evaluate the effectiveness and safety of the ALLON 2001 microprocessor-based thermoregulation system in pediatric patients undergoing cardiac surgery requiring hypothermic cardiopulmonary bypass compared with the routine thermal care. ⋯ The investigated thermoregulation system was effective in preventing the after-drop of temperature that occurs after cardiopulmonary bypass in small infants compared with routine warming methods.