Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Apr 2010
Comparative StudyLongitudinal assessment of neurocognitive function in rats after cardiopulmonary bypass: evidence for long-term deficits.
Neurologic and neurocognitive dysfunction after cardiopulmonary bypass (CPB) have been shown in both clinical and experimental settings. Although short-term outcome has been evaluated in rats, the assessment of neurocognitive dysfunction with long-term follow-up has not been reported in experimental CPB models. The objective of this study was to evaluate the effects of CPB on long-term neurocognitive function in the rat. ⋯ Compared with sham-operated controls, rats undergoing CPB showed worse neurologic and neurocognitive outcome early after surgery. Importantly, long-term deficits also persisted at 6 weeks after surgery.
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J. Cardiothorac. Vasc. Anesth. · Apr 2010
Letter Case ReportsRemifentanil for awake thoracoscopic bullectomy.