Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Dec 2013
Isolated High Lactate or Low Central Venous Oxygen Saturation After Cardiac Surgery and Association with Outcome.
To determine if isolated abnormally low central venous oxygen saturation (ScvO2) or elevated lactate levels on admission to an intensive care unit (ICU) are associated with increased morbidity and length of stay (LOS) after cardiac surgery. ⋯ Low ScvO2 with normal lactate or moderately elevated lactate with normal ScvO2 upon ICU admission after cardiac surgery was not associated with increased morbidity or length of stay. Markedly elevated lactate levels in the setting of a normal ScvO2 was associated with significantly higher incidence of major complications and prolonged length of stay. Additionally, a lactate level ≥ 4 mmol/L was an independent predictor of major complications.
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J. Cardiothorac. Vasc. Anesth. · Dec 2013
Effects of Isoflurane Anesthesia on Aortic Compliance and Systemic Hemodynamics in Compliant and Noncompliant Aortas.
To investigate the effect of general anesthesia on aortic compliance and other cardiovascular hemodynamics in chronically instrumented pigs with compliant and noncompliant (stiff) aortas. ⋯ Induction of general anesthesia caused a similar increase in total arterial compliance and was associated with a decrease in SBP that was more pronounced in animals with noncompliant aortas. These results indicated that anesthesia caused a greater hemodynamic effect on noncompliant (stiff) aortas and may explain the extensive hemodynamic fluctuation and instability often observed in atherosclerotic, elderly patients with stiff aortas.