Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Jan 2022
Dosing of Opioid Medications During and After Pediatric Cardiac Surgery for Children With Down Syndrome.
To determine whether children with Down syndrome (DS) receive higher doses of opioid medications compared with children without DS for repair of complete atrioventricular canal (CAVC). ⋯ These results suggested that patients with DS undergoing CAVC repair do not have increased opioid requirements compared with a similar control group.
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J. Cardiothorac. Vasc. Anesth. · Jan 2022
Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery.
The objective of this study was to identify novel serum biomarkers specific to postoperative delirium after major cardiac surgery to provide insight into the pathologic processes involved in delirium and its sequelae. ⋯ FGF-21, FGF-23, interleukin-6, and monocyte chemotactic protein-3 serum levels were increased postoperatively in patients who developed delirium after major cardiac surgery. This study identified two members of the FGF family as potential putative systemic biomarkers for postoperative delirium after cardiac surgery, suggesting a possible role for metabolic recovery in the pathophysiologic mechanisms underlying neurocognitive dysfunction.