Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Jun 2011
Comparative StudyCefuroxime pharmacokinetics in pediatric cardiovascular surgery patients undergoing cardiopulmonary bypass.
The objective of this study was to determine the pharmacokinetics of cefuroxime in children undergoing cardiopulmonary bypass (CPB) for cardiovascular surgery. ⋯ Manufacturers recommend that pediatric doses of cefuroxime (25-50 mg/kg) can be used in infants and children undergoing CPB to maintain adequate serum concentrations for surgical-site infection prophylaxis. A second intraoperative dose, administered through the CPB circuit, provides no additional prophylactic advantage.
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J. Cardiothorac. Vasc. Anesth. · Jun 2011
Comparative StudyPostoperative increase in B-type natriuretic peptide levels predicts adverse outcome after cardiac surgery.
To evaluate the prognostic implication of changes in postoperative B-type natriuretic peptide (BNP) concentrations in patients undergoing cardiopulmonary bypass for cardiac surgery. ⋯ Elevated BNP levels on admittance to the ICU and postoperatively increasing BNP levels are associated with adverse postoperative outcome and are predictive of impaired late survival. Sequential postoperative BNP monitoring facilitates the early identification of patients at an increased risk of heart failure and may be used as an adjunct for clinical decision making and optimized patient management.
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J. Cardiothorac. Vasc. Anesth. · Jun 2011
Comment Letter Review Comparative StudyTranscatheter aortic valve implantation for high-risk patients does not reduce mortality compared with predicted.
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J. Cardiothorac. Vasc. Anesth. · Jun 2011
Comparative StudyAssessment of trending ability of cardiac output monitors by polar plot methodology.
To develop a valid statistical method of showing acceptable cardiac output (CO) trending ability when new CO monitors are compared to a reference standard, such as thermodilution, using polar coordinates. ⋯ Polar plots can be used to show the trending ability of CO monitors in comparative validation studies. They overcome the deficiencies of concordance analysis, which uses the direction of change as a statistic and ignores the magnitude of change in CO.
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J. Cardiothorac. Vasc. Anesth. · Jun 2011
Letter Case ReportsUnusual variance at the main carina during bronchoscopy.