Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Aug 2008
Randomized Controlled Trial Comparative StudyCardiac protection with volatile anesthetics in stenting procedures.
Myocardial ischemic damage is reduced by volatile anesthetics in patients undergoing coronary artery bypass graft surgery. The authors tested the hypothesis that low-dose sevoflurane could decrease perioperative myocardial damage, as measured by cTnI release, when compared with placebo, in patients undergoing interventional cardiology procedures. ⋯ Myocardial damage measured by cardiac troponin release was not reduced by the volatile anesthetic sevoflurane during interventional cardiology procedures in this study.
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J. Cardiothorac. Vasc. Anesth. · Aug 2008
Comparative StudyPredictors and early and late outcomes of dialysis-dependent patients in contemporary cardiac surgery.
The aim of the study was to investigate the incidence and predictors of renal failure requiring dialysis (RF-D) in a contemporary cohort of patients undergoing cardiac surgery. The authors also analyzed early and late outcome of patients with this complication. ⋯ The authors observed an increase in the overall incidence of RF-D compared with previous studies, probably related to an increased prevalence of patients undergoing more complex procedures with a worsening risk profile. Postoperative RF-D was not only associated with increased hospital mortality and morbidity, but also with a significant reduction of long-term survival in discharged patients. Seven independent predictors of RF-D were identified. Future research efforts should focus on a more precise identification of patients at risk and the development of new treatment modalities, which would potentially prevent the occurrence of this complication.
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J. Cardiothorac. Vasc. Anesth. · Aug 2008
Comparative StudyClosed-loop control of consciousness during lung transplantation: an observational study.
To determine if propofol infusion can be steered automatically by using bispectral index (BIS) as a controller during lung transplantation. ⋯ Closed-loop control of consciousness by a computer during lung transplantation is clinically feasible.
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J. Cardiothorac. Vasc. Anesth. · Aug 2008
Comparative StudyReactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo.
Helium produces preconditioning by activating prosurvival kinases, but the roles of reactive oxygen species (ROS) or mitochondrial adenosine triphosphate-regulated potassium (K(ATP)) channels in this process are unknown. The authors tested the hypothesis that ROS and mitochondrial K(ATP) channels mediate helium-induced preconditioning in vivo. ⋯ The results suggest that ROS and mitochondrial K(ATP) channels mediate helium-induced preconditioning in vivo.