Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Oct 2007
Global end-diastolic volume as a variable of fluid responsiveness during acute changing loading conditions.
Dynamic variables of preload such as stroke volume variation (SVV) have been shown to be good predictors of fluid responsiveness. They are, however, not applicable during spontaneous breathing and cardiac arrhythmias. Volumetric variables of preload, such as global end-diastolic volume (GEDV) and left ventricular end-diastolic area (LVEDA), might be alternative variables of preload to guide fluid administration. Therefore, the present study was designed to evaluate whether GEDV and LVEDA are suitable parameters of preload and fluid responsiveness during rapidly changing loading conditions. ⋯ In this animal model, GEDV and LVEDA were superior to SVV in accurately reflecting hemorrhage. However, GEDV and SVV but not LVEDA were suitable to predict fluid responsiveness.
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J. Cardiothorac. Vasc. Anesth. · Oct 2007
Randomized Controlled Trial Multicenter Study Comparative StudySevoflurane provides earlier tracheal extubation and assessment of cognitive recovery than isoflurane in patients undergoing off-pump coronary artery bypass surgery.
To determine whether sevoflurane, because of its lower blood/gas partition coefficient, compared with isoflurane as the primary anesthetic agent, allows earlier tracheal extubation and assessment of cognitive function after off-pump coronary artery bypass (OPCAB) surgery. ⋯ Both sevoflurane and isoflurane may be safely used as maintenance agents in OPCAB. Sevoflurane has the advantage of allowing earlier extubation and evaluation of cognitive and neurologic function after OPCAB.