Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2007
Randomized Controlled Trial Comparative StudyComparison of nicardipine versus esmolol in attenuating the hemodynamic responses to anesthesia emergence and extubation.
The purpose of this study was to compare the effectiveness of intravenous (IV) nicardipine versus esmolol in controlling heart rate (HR) and blood pressure (BP) responses to emergence and extubation. ⋯ Although esmolol, 1.5 mg/kg, IV was more effective than nicardipine, 0.03 mg/kg, IV for attenuating the HR response to extubation, nicardipine was more effective in controlling the BP response.
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J. Cardiothorac. Vasc. Anesth. · Feb 2007
Clinical TrialThe role of endogenous kallikrein inhibition in perioperative transfusion and adverse outcome in cardiac surgical patients.
The goal of this study was to explore the relationship among endogenous plasma kallikrein inhibition (KI), perioperative bleeding, and adverse outcomes in cardiac surgery. ⋯ Contrary to expectation, higher endogenous KI levels were associated with more blood product transfusion, longer postoperative mechanical ventilation, and hospital length of stay. These findings raise questions as to the role of KI in postoperative outcomes.
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J. Cardiothorac. Vasc. Anesth. · Feb 2007
Clinical TrialTemperature-related differences in mean expired pump and arterial carbon dioxide in patients undergoing cardiopulmonary bypass.
To investigate the relationship between arterial carbon dioxide (PaCO(2)) and mean expired pump CO(2) during cardiopulmonary bypass (PeCPBCO(2)) in patients undergoing cardiac surgery with CPB during steady state, cooling, and rewarming phases of CPB. ⋯ Monitoring the mean expired CO(2) value from the CPB oxygenator exhaust scavenging port with a capnography monitor provides a continuous and noninvasive data source to aid in sweep flow CPB circuit management during CPB.
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J. Cardiothorac. Vasc. Anesth. · Feb 2007
Editorial CommentStrengths and limitations of meta-analysis.