Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Randomized Controlled Trial Comparative Study Clinical TrialComparison of three remifentanil dose-finding regimens for coronary artery surgery.
To identify the remifentanil dosing regimen providing safe and optimal anesthetic conditions during coronary artery bypass graft surgery and to evaluate postoperative recovery characteristics. ⋯ After lorazepam premedication, remifentanil infusion (2-4 microg/kg/min) supplemented intermittently with low inspired concentrations of isoflurane provided an effective anesthetic regimen for coronary artery bypass graft surgery. Early extubation times were feasible after remifentanil continuous infusions (1-5 microg/kg/min) used as the primary anesthetic component intraoperatively and for analgesia (
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Comparative Study Clinical TrialThe effects of remifentanil and thoracic epidural on oxygenation and pulmonary shunt fraction during one-lung ventilation.
To compare the effects of remifentanil and thoracic epidural analgesia on the hemodynamic changes and pulmonary shunt fraction during one-lung ventilation (OLV) for thoracotomy. ⋯ Both remifentanil infusion and TEA are suitable for analgesia during thoracic surgery when OLV is used. There was no significant difference in PaO(2) and Qs/Qt during each administration.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Is very early extubation after lung transplantation feasible?
To evaluate donor graft function, intraoperative blood consumption, and oxygenation and hemodynamic stability in patients undergoing lung transplantation. ⋯ The use of a short-acting anesthetic drug, appropriate intraoperative extubation criteria, epidural analgesia, and postoperative noninvasive ventilation make early extubation of lung-transplanted patients possible and effective.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Are serum S100beta proteins and neuron-specific enolase predictors of cerebral damage in cardiovascular surgery?
To examine whether serum concentrations of S100beta protein and neuron-specific enolase (NSE) are predictors of cerebral damage in cardiovascular surgery. ⋯ A large part of the increases in S100beta protein and NSE during CPB and SCP is not attributed to neuronal damage, but to contamination with the blood from the surgical field. To determine whether these markers are useful to predict neurologic complications, it will be necessary to exclude contamination from the surgical field as observed in the present study.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Comparative StudyLung perfusion, shunt fraction, and oxygenation during one-lung ventilation in pigs: the effects of desflurane, isoflurane, and propofol.
To study how desflurane, isoflurane, and propofol affect pulmonary perfusion, shunt fraction, and systemic oxygenation during one-lung ventilation (OLV) in vivo. ⋯ In a clinically relevant model of OLV cardiac output, PaO(2) and mixed venous PO(2) decreased during desflurane and isoflurane as compared with propofol, whereas perfusion of the nonventilated lung and shunt fraction remained comparable.