Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Jun 2000
The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium.
To evaluate the effect of the 5-HT3-receptor antagonist ondansetron in patients with postcardiotomy delirium. ⋯ The use of ondansetron was effective and safe and without important side effects. This positive effect of the 5-HT3-receptor antagonist ondansetron led to speculation that impaired serotonin metabolism may play a role in postcardiotomy delirium.
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J. Cardiothorac. Vasc. Anesth. · Jun 2000
ReviewAnesthesia for left ventricular assist device placement.
Appropriate anesthesia for LVAD placement needs to incorporate an understanding of the surgical procedure and LVAD physiology, the altered physiology and pharmacology of the cardiac failure patient, and a knowledge of the interaction of anesthesia with the potent cardiac drugs used in end-stage heart failure therapy. The anesthesiologist is faced with a critically ill decompensated patient, often with altered renal and hepatic function, but must ensure adequate anesthesia to avoid intraoperative awareness. Intelligent use of TEE can assist the surgeon to pinpoint potential pitfalls of LVAD placement and can have a significant effect on improving outcome in these challenging patients.