Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Dec 1995
Cerebral complications after cardiac surgery assessed by S-100 and NSE levels in blood.
Assessment of the value of blood analysis of the astroglia protein, S-100, and neuron-specific enolase for the detection of nervous system dysfunction after cardiac surgery. ⋯ S-100 and neuron-specific enolase levels after cardiac surgery are associated with neurologic complications. The results have implications on patient-related treatment and prognosis as well as for the development of safer perfusion techniques.
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J. Cardiothorac. Vasc. Anesth. · Dec 1995
Comparative StudyComparison of the alteration of cardiac function by sevoflurane, isoflurane, and halothane in the isolated working rat heart.
Despite its widespread use, little is known about sevoflurane's physiologic effects. The direct myocardial effects of sevoflurane were compared with both halothane and isoflurane. ⋯ These data suggest that sevoflurane depresses cardiac function less than either halothane in doses of 1.0 and 1.5 x MAC or isoflurane at doses of 3 x MAC.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Randomized Controlled Trial Comparative Study Clinical TrialPain outcomes after thoracotomy: lumbar epidural hydromorphone versus intrapleural bupivacaine.
To evaluate postthoractomy analgesia in patients receiving lumbar epidural hydromorphone versus intrapleural bupivacaine. ⋯ Epidural hydromorphone is superior to intrapleural bupivacaine in achieving satisfactory pain outcomes during the first 5 hours after thoracotomy.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Randomized Controlled Trial Clinical TrialLidocaine and the inhibition of postoperative pain in coronary artery bypass patients.
This study was designed to evaluate whether a continuous low-dose lidocaine infusion reduces postoperative pain and anxiety in patients undergoing coronary artery bypass grafting (CABG) and to retrospectively examine time to extubation, intensive care unit stay (ICU), and hospital length of stay. ⋯ Continuous infusion of low-dose lidocaine did not significantly decrease supplemental fentanyl, midazolam, or propranolol requirement postoperatively. Similarly, a lidocaine infusion does not result in reduced time to extubation. ICU stay, or hospital length of stay.