Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Dec 1995
Randomized Controlled Trial Comparative Study Clinical TrialEffects of a paf-receptor antagonist on hemodynamics during and after cardiopulmonary bypass.
To assess after cardiopulmonary bypass (CPB) the role of paf-acether (paf), a phospholipid mediator whose injection in animal mimics the hemodynamics observed after CPB. ⋯ Because the inotropic and vasodilator therapy and the volume loading were the same between groups, this study suggests that pretreatment with a paf-receptor antagonist improves post-CPB pulmonary resistance. Nevertheless, this beneficial effect is transient without consequences on left ventricular function indices.
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J. Cardiothorac. Vasc. Anesth. · Dec 1995
Cerebral complications after cardiac surgery assessed by S-100 and NSE levels in blood.
Assessment of the value of blood analysis of the astroglia protein, S-100, and neuron-specific enolase for the detection of nervous system dysfunction after cardiac surgery. ⋯ S-100 and neuron-specific enolase levels after cardiac surgery are associated with neurologic complications. The results have implications on patient-related treatment and prognosis as well as for the development of safer perfusion techniques.
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J. Cardiothorac. Vasc. Anesth. · Dec 1995
Comparative StudyThe relationship between systolic pressure and stroke volume describes myocardial contractility.
To develop a method of measuring end-systolic elastance from information obtained outside the ventricle and thereby simplify its transduction. ⋯ In this study, measurement of EES from the ventricular outflow tract during progressive aortic constriction produced results more consistent and descriptive than EES by traditional techniques and has the potential for obtaining elastance measurements from possibly less invasive techniques.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Determinants of systolic pressure variation in patients ventilated after vascular surgery.
To discover the predominant determinant of systolic pressure variation during positive-pressure ventilation in mechanically ventilated patients after a vascular surgical procedure. ⋯ The decrease in systolic pressure provoked by positive-pressure inspiration reflects simultaneous decreases in stroke volume. This suggests that a decrease in left ventricular filling, associated with positive-pressure inspiration, is responsible for systolic pressure variation. This finding confirms the interest in considering systolic pressure variation to provide reliable information about the responsiveness of the heart to preload variations.