European radiology
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Comparative Study
Comparison of lung imaging using three-dimensional ultrashort echo time and zero echo time sequences: preliminary study.
To determine the feasibility of using high-resolution volumetric zero echo time (ZTE) sequence in routine lung magnetic resonance imaging (MRI) and compare free breathing 3D ultrashort echo time (UTE) and ZTE lung MRI in terms of image quality and small-nodule detection. ⋯ • Both UTE and ZTE techniques use very short TEs to capture signals from very short T2/T2* tissues. • ZTE is superior in capturing lung parenchymal signal than UTE. • ZTE provides high-resolution structural information with better SNR and CNR for normal intrapulmonary structures and small nodules using shorter scan time than UTE.
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To investigate the structural changes of the brain that correlate with physical frailty and cognitive impairments in Parkinson's disease (PD) patients. ⋯ • Physical frailty in PD was associated with decreased GMV in the frontal and occipital cortices, while cognitive impairment was associated with decreased GMV in the frontal, temporal, and occipital cortices. • Physical frailty and cognitive impairment were both associated with decreased GMV in the lateral occipital cortex, which is part of the ventral object-based visual pathway. • Decreased GMV in the lateral occipital cortex may serve as a potential imaging biomarker for physical frailty and cognitive impairment in PD.
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The aim of this study was to develop a radiomics nomogram by combining the optimized radiomics signatures extracted from 2D and/or 3D CT images and clinical predictors to assess the overall survival of patients with non-small cell lung cancer (NSCLC). ⋯ • We found both 2D and 3D radiomics signature have favorable prognosis, but 3D signature had a better performance. • The radiomics signature generated from the combined 2D and 3D features had a better predictive performance than those from 2D or 3D features. • Integrating the optimal radiomics signature with clinical predictors significantly improved the predictive power in patients' survival compared with clinical TNM staging alone.
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This study aimed to evaluate the clinical feasibility of catheter-directed selective computed tomography angiography (S-CTA) in patients with coronary artery disease (CAD). ⋯ • Selective computed tomography angiography (S-CTA) can serve as an intraprocedural computed tomography angiography protocol. • S-CTA was performed with low dose of iodine compared with conventional computed tomography angiography. • S-CTA enables on-site atherosclerotic plaque analysis.
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To investigate brain microstructural changes in white matter and gray matter of type 2 diabetes mellitus (T2DM) patients using diffusion kurtosis imaging. ⋯ • Diffusion kurtosis imaging detects more brain regions with microstructural alterations in white matter and gray matter of T2DM patients than DTI. • Mean kurtosis changes are associated with disease severity and impaired neuropsychological function in T2DM. • Diffusion kurtosis imaging demonstrates potential to assess cognitive impairment in T2DM patients and predict disease progression.