European radiology
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The aim of this study was to develop a radiomics nomogram by combining the optimized radiomics signatures extracted from 2D and/or 3D CT images and clinical predictors to assess the overall survival of patients with non-small cell lung cancer (NSCLC). ⋯ • We found both 2D and 3D radiomics signature have favorable prognosis, but 3D signature had a better performance. • The radiomics signature generated from the combined 2D and 3D features had a better predictive performance than those from 2D or 3D features. • Integrating the optimal radiomics signature with clinical predictors significantly improved the predictive power in patients' survival compared with clinical TNM staging alone.
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Comparative Study
Comparison of lung imaging using three-dimensional ultrashort echo time and zero echo time sequences: preliminary study.
To determine the feasibility of using high-resolution volumetric zero echo time (ZTE) sequence in routine lung magnetic resonance imaging (MRI) and compare free breathing 3D ultrashort echo time (UTE) and ZTE lung MRI in terms of image quality and small-nodule detection. ⋯ • Both UTE and ZTE techniques use very short TEs to capture signals from very short T2/T2* tissues. • ZTE is superior in capturing lung parenchymal signal than UTE. • ZTE provides high-resolution structural information with better SNR and CNR for normal intrapulmonary structures and small nodules using shorter scan time than UTE.
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To investigate the structural changes of the brain that correlate with physical frailty and cognitive impairments in Parkinson's disease (PD) patients. ⋯ • Physical frailty in PD was associated with decreased GMV in the frontal and occipital cortices, while cognitive impairment was associated with decreased GMV in the frontal, temporal, and occipital cortices. • Physical frailty and cognitive impairment were both associated with decreased GMV in the lateral occipital cortex, which is part of the ventral object-based visual pathway. • Decreased GMV in the lateral occipital cortex may serve as a potential imaging biomarker for physical frailty and cognitive impairment in PD.
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To evaluate predictive values of sarcopenia and visceral obesity measured from preoperative CT/MRIs for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy in patients with periampullary malignancies. ⋯ • Sarcopenic obesity might be predictive for postoperative pancreatic fistula after pancreaticoduodenectomy. • The vascular resection during pancreaticoduodenectomy might be predictive of major complications. • Body morphometric analysis might be helpful for identifying high-risk patients.
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Multicenter Study Comparative Study Observational Study
The value of post-mortem computed tomography of burned victims in a forensic setting.
Fire deaths are challenging fatalities for forensic pathologists, as the main question of whether death was due to the fire or not needs to be answered. In this retrospective study, we assessed whether post-mortem computed tomography (PMCT) has an added value prior to a forensic autopsy of burned victims. ⋯ • Post-mortem CT (PMCT) in burned victims shows hidden signs of trauma. • Foreign bodies and gas collections can easily be detected. • Cause of death and vitality signs cannot be assessed by PMCT.