International journal of obstetric anesthesia
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Int J Obstet Anesth · Apr 2004
Comparative StudyIn vitro evidence of gender-related heparin resistance.
Coagulability varies among men, women, and pregnant women, along a spectrum where the blood of men is the least and that of pregnant women the most coagulable. The effects of differences in coagulation status on the action of heparin cannot be measured by specific laboratory tests such as aPTT or anti-Factor Xa assay. Thromboelastography which measures whole blood coagulation can assess the effect of heparin against differing backgrounds of coagulation. ⋯ Across the subject groups, from men to pregnant women, increasing coagulability was seen, with shortening of r and k (P < 0.04), and increasing angle and MA (P < 0.0001). A relationship between gender and heparin was significant for r and k (P < 0.02) but not for angle and MA. This result assists the case against a one-size-fits-all approach to policies on heparinisation.
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Int J Obstet Anesth · Apr 2004
Case ReportsAnaesthesia for caesarean section in a patient with syringomyelia and Arnold-Chiari type I malformation.
A 37-year-old primiparous woman with syringomyelia and Arnold-Chiari type I malformation was scheduled to undergo elective caesarean section for a fetus in the breech presentation. Caesarean section was performed under general anaesthesia without complications; all we observed was an exaggerated response to atracurium. ⋯ Syringomyelia is a progressive myelopathy characterised by cystic degeneration within the spinal cord, which causes severe neurological deficits. The anaesthetic management is discussed.
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Int J Obstet Anesth · Apr 2004
Comment Letter Case ReportsMore failed spinal anesthetics with hyperbaric bupivacaine.
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Int J Obstet Anesth · Apr 2004
Comment Letter Case ReportsInadequate spinal anaesthesia with 0.5% Marcain Heavy (Batch 2016).