International journal of obstetric anesthesia
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Int J Obstet Anesth · Jan 2013
Intrathecal morphine 100 and 200 μg for post-cesarean delivery analgesia: a trade-off between analgesic efficacy and side effects.
Intrathecal morphine is highly effective for post-cesarean analgesia; however, the optimal dose is yet to be established. The aim of this study was to compare analgesia and side effects after a change in institutional practice to give 200 μg rather than 100 μg. ⋯ Intrathecal morphine 200 μg provided better analgesia but with more nausea compared with morphine 100 μg. Our results can be used to help guide intrathecal morphine dosing in cesarean delivery based on patient preference for analgesia versus side effects.
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Int J Obstet Anesth · Jan 2013
Choice of anaesthetic agents for caesarean section: a UK survey of current practice.
A national survey of current practice and preferred drug choices for both induction and maintenance of general anaesthesia for caesarean section was undertaken. ⋯ Our survey suggests that while thiopental remains the induction agent of choice in the UK, a reasonable body of medical opinion would support a change to propofol for induction. This is reassuring as thiopental becomes more difficult and expensive to obtain.
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Int J Obstet Anesth · Jan 2013
The impact of spinal anaesthesia for caesarean delivery on coagulation assessed by thromboelastography.
Pregnancy and puerperium are associated with a hypercoagulable state. The aim of the study was to assess the impact of spinal anaesthesia on coagulation using thromboelastography in healthy term pregnant women undergoing elective caesarean delivery. ⋯ In women undergoing caesarean delivery under spinal anaesthesia, enhanced coagulation thromboelastography parameters were observed in blood collected from hand veins. No changes were detected in the majority of parameters collected from the foot. Spinal anaesthesia has different effects on coagulation parameters in the hand and foot in pregnant women undergoing caesarean delivery.