International journal of obstetric anesthesia
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Int J Obstet Anesth · Oct 1999
Randomized Controlled Trial Clinical TrialDose response study of subarachnoid diamorphine for analgesia after elective caesarean section.
Subarachnoid diamorphine provides excellent analgesia after elective caesarean section but the optimum dose is still uncertain. We therefore investigated the effects of three regimens of subarachnoid diamorphine. Forty parturients were assigned to one of four groups. ⋯ The mean (SD) dose of PCA morphine used over 24 h was 39.4 (14.7), 25.6 (16.5), 21.6 (15.9) and 3.1 (3.6) mg, and mean time to first use of morphine was 1.6 (0.5), 3.0 (1.4), 3.4 (2.4) and 14.1 (9.4) h, in the 0, 0.1 mg, 0.2 mg and 0.3 mg groups respectively. Side-effects of pruritus, nausea and vomiting were dependent on the dose of spinal diamorphine but did not require treatment in any patients. We conclude that 0.3 mg subarachnoid diamorphine provides significantly better postoperative pain relief than the smaller doses with an acceptable increase in side-effects.
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Int J Obstet Anesth · Oct 1999
Anaesthetic management of parturients with the antiphospholipid syndrome: a review of 27 cases.
A description of antiphospholipid syndrome (APS) and associated maternal and fetal complications is presented along with a review of the management at National Women's Hospital (NWH), Auckland, of 27 pregnancies complicated by APS. Because the obstetric outcome for parturients with APS continues to improve, anaesthetists are more likely to become involved in their management. It is recommended that policies and protocols are implemented to avoid unnecessary denial of regional anaesthesia arising from confusion about any parturients anticoagulation status.
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Int J Obstet Anesth · Oct 1999
Regional anaesthesia for multiple caesarean sections in a parturient with osteogenesis imperfecta.
We describe a 27-year-old woman with osteogenesis imperfecta who, over a period of 9 years, underwent five caesarean sections under regional anaesthesia without major complication. The first three operations were conducted under epidural and the last two under spinal anaesthesia. To our knowledge, this is the first reported case of spinal anaesthesia for caesarean section in a parturient with osteogenesis imperfecta.