Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Multicenter Study
SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia.
Existing severity assessment tools, such as the pneumonia severity index (PSI) and CURB-65 (tool based on confusion, urea level, respiratory rate, blood pressure, and age >or=65 years), predict 30-day mortality in community-acquired pneumonia (CAP) and have limited ability to predict which patients will require intensive respiratory or vasopressor support (IRVS). ⋯ SMART-COP is a simple, practical clinical tool for accurately predicting the need for IRVS that is likely to assist clinicians in determining CAP severity.
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Comparative Study
Comparison of the clinical effectiveness of oseltamivir and zanamivir against influenza virus infection in children.
We compared the clinical effectiveness of oseltamivir and zanamivir in children with influenza A (H1N1) virus, influenza A (H3N2) virus, and influenza B virus infections. ⋯ Oseltamivir and zanamivir were equally effective in reducing the febrile period of children with influenza A (H1N1), influenza A (H3N2), and influenza B virus infection.