ASAIO journal : a peer-reviewed journal of the American Society for Artificial Internal Organs
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As a brain protection strategy, antegrade selective cerebral perfusion (ASCP) is widely used in thoracic aorta surgery with deep hypothermic circulatory arrest (DHCA), yet the oxygen management for ASCP has never been standardized. The aim of this study was to investigate the possible neuroprotective effects of hyperoxia management during deep hyperthermia for ASCP combined with DHCA in a rabbit model. Rabbits were assigned into four groups: sham group, without cardiopulmonary bypass (CPB); DHCA group, DHCA for 80 minutes; ASCP group, ASCP combined with DHCA; and SH group, hyperoxia management combined with ASCP and DHCA. ⋯ S100 calcium binding protein B in the SH group was lower compared with the DHCA group and the ASCP group (p < 0.05). There was no significant difference of neuron-specific enolase in the SH group compared with the sham group. Hyperoxia management during deep hypothermia provided substantial dissolved oxygen and demonstrated better cerebral protection over normoxia management.
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Case Reports
Accidental cannulation of the left ascending lumbar vein through femoral access-still often unrecognized.
The femoral vein approach is considered to be a quick and safe route for venous access. However, severe complications can occur with this access because of misplacement. ⋯ Clinicians should be aware of possible misplacement while inserting a femoral vein catheter, especially on the left side. In some cases, the correct position in the inferior vena cava needs confirmation before using the catheter.