Acta paediatrica
-
To test that age is of influence on midazolam requirements during prolonged mechanical ventilation in critically ill children. ⋯ Our data showed that children between 1 and 4 years needed higher doses of midazolam as compared to children who were younger and older. Furthermore, we observed that midazolam alone is a poor sedative for all age groups. The influence of and mechanisms for possible age related effects on midazolam requirements remain to be elucidated, as well as the position of midazolam as a first line drug for PICU sedation.
-
Randomized Controlled Trial
Oral glucose as an analgesic to reduce infant distress following immunization at the age of 3, 5 and 12 months.
To evaluate oral glucose as an analgesic to reduce infant distress after immunization during the first year of life and to investigate if these effects change during this period. ⋯ Sweet solution can be used as a simple and safe method to reduce the distress following immunization in infants up to 12 months.
-
To compare known risk factors for sudden infant death syndrome (SIDS) amongst infants with apparent life threatening events (ALTE) with their matched controls, and ALTE infants who subsequently died of SIDS with infants surviving an ALTE. ⋯ Our results show some major differences between the ALTE infants and SIDS victims not supporting that these conditions belong to the same entity. However, we cannot exclude the possibility that there is a subpopulation of ALTE infants who did not die in SIDS due to that they were sleeping on the back and not exposed to nicotine.
-
To test the hypothesis that in volume targeted ventilation modes, ventilator performance would vary according to ventilator type. ⋯ In volume targeted ventilation modes, performance differs between neonatal ventilator types; these results may have implications for clinical practise.
-
To describe severe alarms on home-documented monitoring in infants born prematurely. ⋯ Prematurely born infants with an abnormal polysomnography at discharge are at high risk for developing acute events at home. A younger PMA at birth correlates with a higher risk of alarms at a later PCA.