Acta paediatrica
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Randomized Controlled Trial
The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children.
To determine the efficacy of prophylactic administration of zinc sulphate in reducing the occurrence of the common cold in children, and to evaluate the efficacy of zinc sulphate in reducing the duration and severity of cold symptoms. ⋯ Zinc sulphate appears to be an easily administered, safe and well-tolerated alternative for the prevention and treatment of the common cold in children.
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A 7-y-old, right-handed girl presented at our clinic with complex partial seizures, behavioural problems and word-finding difficulties. Clinical examination was normal, but electroencephalogram revealed bilateral epileptic discharges in the temporal and paracentral leads. Magnetic resonance imaging showed an intracerebral mass in the left mesial temporal lobe in the areas of the gyrus temporooccipitalis medialis and gyrus parahippocampalis. Neuropsychological testing brought to light an above-average general intelligence, but the girl performed below average in verbal memory tests and average in figural memory tests. ⋯ After resection of a left temporal brain tumour, the patient was free of seizures, and neuropsychological functions recovered completely within weeks.
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Vasopressin in catecholamine-resistant septic and cardiogenic shock in very-low-birthweight infants.
To evaluate vasopressin as a rescue therapy in catecholamine-refractory septic and cardiogenic shock in very-low-birthweight (VLBW) infants. ⋯ Although vasopressin appears to be a suitable rescue therapy in catecholamine-resistant septic shock in VLBW infants, further evaluation in controlled clinical trials is warranted.
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Morphine can be used to treat pain in preterm neonates with CPAP because of its analgetic potency; however, it is known to induce apnoea. ⋯ Morphine in preterm infants with CPAP is not widely accepted practice until further randomized studies evaluate efficacy and safety. Morphine in a low dosage (
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We have developed an automated algorithm to allow the measurement of respiratory rate directly from the photoplethysmogram (pulse oximeter waveform). ⋯ Our automated algorithm allows the accurate determination of respiratory rate from photoplethysmograms of a heterogeneous group of children. We believe that our automated wavelet-based signal-processing techniques could soon be easily incorporated into current pulse oximetry technology.