American journal of surgery
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Multicenter Study
Local variations in the epidemiology, microbiology, and outcome of necrotizing soft-tissue infections: a multicenter study.
Necrotizing soft-tissue infections (NSTIs) are rare and highly lethal. ⋯ Significant center differences occur in patient populations, etiology, and microbiology of NSTIs, even within a concentrated region. Management should be based on these characteristics given that adjunctive treatments are unproven and variations in outcome are likely because of patient disease at presentation.