Paediatric anaesthesia
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Paediatric anaesthesia · Feb 2005
Letter Case ReportsAnesthetic management of a child with Aicardi syndrome.
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Paediatric anaesthesia · Feb 2005
Randomized Controlled Trial Comparative Study Clinical TrialCaudal additives for postoperative pain management in children: S(+)-ketamine and neostigmine.
The aim of the present pilot study was to compare the analgesic efficacy of S(+)-ketamine either alone or in combination with neostigmine for caudal blockade in pediatric surgery. ⋯ This pilot study demonstrates equianalgesic effects on postoperative pain relief in children with both caudal S(+)-ketamine 1 mg.kg(-1) and caudal S(+)-ketamine 0.5 mg.kg(-1) plus neostigmine 10 microg.kg(-1). Further studies are required to confirm adoption of caudal neostigmine into routine clinical practice.
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Paediatric anaesthesia · Feb 2005
Clinical TrialSpontaneous ventilation with remifentanil in children.
Remifentanil is a short-acting drug that allows us to study the specific respiratory effects of potent opioid analgesics. The purpose of this study is to describe the effects of a remifentanil infusion during spontaneous ventilation in children. Pharmacokinetic studies provide useful information on the time course of opioid blood concentrations; however, they cannot be easily translated into infusion administration guidelines for pediatric clinical practice. ⋯ There is a large variation in the dose of remifentanil tolerated by children while breathing spontaneously under anesthesia. A respiratory rate of <10 b.min(-1) appears to be the best predictor of the maximum tolerated dose.
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Paediatric anaesthesia · Feb 2005
Clinical TrialIntravenous ketamine sedation for painful oncology procedures.
The aim of the study was to determine the efficacy and adverse effects of intravenous (i.v.) ketamine sedation administered by nonanesthetist physicians for painful procedures. ⋯ Ketamine i.v. up to 2 mg.kg(-1) is an effective sedative for oncology procedures using a defined protocol.