Paediatric anaesthesia
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Paediatric anaesthesia · Jan 2007
Case ReportsBradycardia with sevoflurane in siblings with Branchio-oto-renal syndrome.
Branchio-oto-renal syndrome (BOR, Melnick-Fraser syndrome, MIM#113650) refers to a rare autosomal dominant disorder characterized by branchial cysts or fistulas, hearing loss, external ear malformation, preauricular pits and renal abnormalities. The authors present three episodes of significant bradycardia in two siblings diagnosed with BOR syndrome during the sevoflurane general anesthesia. ⋯ Bradycardia occurred variously at induction, maintenance and immediately prior to emergence and required surgical stimulation, atropine, or epinephrine to treat. We seek to raise awareness of the potential for bradycardia during the procedures in patients with this syndrome requiring volatile anesthesia, especially sevoflurane.
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Paediatric anaesthesia · Jan 2007
The risk of malignant hyperthermia in children undergoing muscle biopsy for suspected neuromuscular disorder.
It is assumed that those children with known or suspected neuromuscular disorders (NMD) are at increased risk for malignant hyperthermia (MH). Despite the lack of conclusive data, most of these children are managed with a nontriggering anesthetic. This study examined the risk of MH in children exposed to a triggering anesthetic while undergoing muscle biopsy for suspected NMD. ⋯ The estimated risk of MH or rhabdomyolysis is 1.09% or less in a diverse population of children with suspected NMD.
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Paediatric anaesthesia · Jan 2007
Letter Case ReportsAnesthetic management in a child with deletion 9p syndrome.