Paediatric anaesthesia
-
Paediatric anaesthesia · Oct 2011
Randomized Controlled TrialChildren on phenobarbital monotherapy requires more sedatives during MRI.
Phenobarbital induces specific hepatic cytochrome P-450 enzyme pathways causing increased clearance of hepatically metabolized drugs. In this study, we investigated the duration and additional anesthetic requirement during Magnetic resonance imaging (MRI) in epileptic children with or without phenobarbital monotherapy. ⋯ We suggest that the variability in response to the initial sedative agents during MRI requires titration of additive sedation with ketamine in epileptic children on phenobarbital monotherapy.
-
Paediatric anaesthesia · Oct 2011
Randomized Controlled TrialThe perioperative dialogue reduces postoperative stress in children undergoing day surgery as confirmed by salivary cortisol.
To evaluate the efficacy of 'the perioperative dialogue (PD)' by analyzing salivary cortisol, in 5- to 11-year-old children undergoing day surgery. ⋯ The PD's caring, continuity, and on-going dialogues were associated with low concentrations of salivary cortisol postoperatively and reduced morphine consumption and thus appears to be a valuable complement to standard perioperative care in children undergoing day surgery.