Paediatric anaesthesia
The most recent articles from:
Paediatr Anaesth
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Paediatric anaesthesia · Jun 2021
Prediction of levobupivacaine concentrations in neonates and infants following neuraxial rescue blocks.
Pharmacokinetic simulation was used to characterize levobupivacaine disposition after regional anesthetic rescue for failed spinal anesthesia in neonates and infants. ⋯ Total bupivacaine concentrations greater than 2.5 mg L-1 are associated with neurotoxicity in adults. Predicted concentrations after either a repeat spinal or a caudal rescue dose of levobupivacaine 1.5 mg kg-1 1 h after spinal levobupivacaine administration are below the neurotoxic concentration threshold.
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Paediatric anaesthesia · Jun 2021
Comparative Study Observational StudyAnesthetic Outcomes in Pediatric Patients with COVID-19: A Matched Cohort Study.