Paediatric anaesthesia
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Paediatric anaesthesia · Oct 2020
Case ReportsAnesthetic Implications of a Pediatric Patient with Stiff Skin Syndrome: A Case Report.
Stiff skin syndrome is a rare genetic disorder that is present in infancy or early childhood. It is characterized by hard, inflexible skin and limited joint mobility making anesthetic management of these patients challenging. ⋯ Even though peripheral intravenous access can be relatively easy, central venous cannulation may be problematic due to the hard skin overlying the entry sites. Our case report details the anesthetic management and considerations of a pediatric patient with stiff skin syndrome.
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Paediatric anaesthesia · Oct 2020
Femoral Nerve Catheters Are Associated with Limb Strength Asymmetry at 6 Months After Primary Anterior Cruciate Ligament Reconstruction in Pediatric Patients.
The postoperative implications of single-injection femoral nerve blockade and femoral nerve catheter placement for anterior cruciate ligament reconstruction are not well defined among pediatric patients. Femoral nerve blockade may be associated with deficits in quadriceps symmetry at 6 months postoperative. ⋯ Though time to return to sport did not differ, patients in the femoral nerve catheter group exhibited greater single-leg squat asymmetry than did those in the femoral nerve blockade group approximately 6 months postoperatively. Persistent functional deficits may be important to consider when treating pediatric patients undergoing anterior cruciate ligament reconstruction.
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Paediatric anaesthesia · Oct 2020
Observational StudyHydromorphone Population Pharmacokinetics in Pediatric Surgical Patients.
Hydromorphone is an opioid agonist used for pediatric analgesia. Due to lack of data, pediatric dosing (based on adult pharmacokinetic models) is not optimal. ⋯ After intravenous hydromorphone, plasma pharmacokinetic profiles in children undergoing different surgeries were well described by a two-compartment population allometric pharmacokinetic model using bodyweight as the size descriptor. Model informed simulations identified patient-controlled analgesia parameters to inform initial settings, with adjustments as needed based on observed individual effects.