Paediatric anaesthesia
The most recent articles from:
Paediatr Anaesth
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Paediatric anaesthesia · Jun 2016
Randomized Controlled TrialDextrose-containing intraoperative fluid in neonates: a randomized controlled trial.
Glucose requirement in neonates during surgery and the impact of glucose supplementation on neonatal metabolism remain unclear. ⋯ All three solutions, when infused at 10 ml·kg(-1) ·h(-1) , are equally effective in maintaining glucose homeostasis, but 1% dextrose-containing fluid promotes catabolism, insulin resistance, rebound hyperglycemia, and acidosis. Therefore, 2-4% dextrose-containing fluids is more suitable compared to 1% dextrose-containing fluids for use during major neonatal surgeries requiring average fluid infusion rate of 10 ml·kg(-1) ·h(-1) .