Paediatric anaesthesia
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A enjoyable trip down memory lane with Prof. Kester Brown. A brief description of the history of barbiturates and their structure activity relationships, culminating in the seven decade dominance of thiopentone.
The second half of this paper briefly describes the drugs that have challenged thiopentone, those you will likely have used (propofol, etomidate) and those most likely not (propanidid, althesin, gamma-hydroxybutyrate).
An quick and enjoyable read. Click through for the full-text.
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Paediatric anaesthesia · Oct 2013
Randomized Controlled Trial Comparative StudyA randomized controlled comparison of the Bonfils fiberscope and the GlideScope Cobalt AVL video laryngoscope for visualization of the larynx and intubation of the trachea in infants and small children with normal airways.
The Bonfils fiberscope (BF) used without the assistance of a laryngoscope failed to improve the view of direct laryngoscopy in children with normal airways. We hypothesized that if BF is supported by a laryngoscope--as recommended by its inventor--it can provide comparably good visualization of the glottis as the GlideScope(®) Cobalt AVL video laryngoscope (GS). ⋯ The Bonfils fiberscope significantly improved the view on the larynx compared with direct laryngoscopy and the GlideScope and enables shorter intubation time than with the GlideScope.
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Paediatric anaesthesia · Oct 2013
Case ReportsContinuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Different transversus abdominis plane blocks techniques cause variations in postoperative analgesia characteristics. We report the use of unilateral quadratus lumborum catheter for analgesia following colostomy closure. ⋯ No complications were reported in this pediatric patient. More studies are needed to evaluate the effectiveness and safety of this regional anesthesia technique.
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Paediatric anaesthesia · Oct 2013
Comparative StudyIntravenous versus intramuscular epinephrine administration during cardiopulmonary resuscitation - a pilot study in piglets.
Early epinephrine administration in cardiac arrest seems to be advantageous to achieve return of spontaneous circulation (ROSC). Because intravenous (i.v.) or intraosseous access is not always immediately available, this study compares efficacy of early intramuscular (i.m.) epinephrine administration with early and delayed i.v. epinephrine injection in an animal cardiac arrest model. ⋯ Early i.m. epinephrine provided similar survival compared with early i.v. epinephrine and was superior to delayed epinephrine administration in resuscitation of ropivacaine-induced cardiac arrest in piglets.