Paediatric anaesthesia
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Paediatric anaesthesia · Jul 2012
Perioperative course of FXIII in children undergoing major surgery.
Acquired deficiency of FXIII because of perioperative hemodilution has been described several times in adults; however, data in children are scarce. We performed a prospective observational trial to evaluate the intraoperative course of FXIII in children undergoing elective major surgery. ⋯ Coagulation factor XIII decreased early during major surgery owing to hemodilution. Overall intraoperative FXIII levels remain low despite of transfusion of fresh frozen plasma.
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Paediatric anaesthesia · Jul 2012
Geographic differences in perioperative opioid administration in children.
To investigate whether geographic differences exist in perioperative opioid administration to children. ⋯ Children in Central and South America received less opioid intraoperatively than African and Indian children, under standardized anesthesia for cleft surgeries. Further research is necessary to elucidate the mechanisms underlying these group differences.
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Paediatric anaesthesia · Jul 2012
Is ethnicity associated with morphine's side effects in children? Morphine pharmacokinetics, analgesic response, and side effects in children having tonsillectomy.
To examine whether morphine pharmacokinetics (PK) and/or genetic polymorphisms in opioid-related genes, underlie differences in analgesic response and side effects to morphine in Latino (L) vs non-Latino Caucasian (NL) children. ⋯ We found statistically significant differences in the occurrence of side effects after morphine administration between L and NL children. Neither differences in morphine or metabolite concentrations, nor the genetic polymorphisms examined explain these findings. Studies are needed to further investigate reasons for the increase in morphine side effects by Latino ethnicity.
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Paediatric anaesthesia · Jul 2012
Biography Historical ArticleToivo Suutarinen--father of Finnish pediatric anesthesia.
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Paediatric anaesthesia · Jul 2012
Acupuncture therapy for infants: a preliminary report on reasons for consultation, feasibility, and tolerability.
The aim of this retrospective review was to determine the feasibility, safety, and potential therapeutic effects of acupuncture in an inpatient infant population and to obtain data that would support the design of a randomized, controlled trial of acupuncture in infants. ⋯ In this small group of hospitalized infants, acupuncture was found to be safe, well tolerated, and therapeutic. More studies are warranted to define the role of acupuncture in this population.