Paediatric anaesthesia
-
Paediatric anaesthesia · Jul 2012
Geographic differences in perioperative opioid administration in children.
To investigate whether geographic differences exist in perioperative opioid administration to children. ⋯ Children in Central and South America received less opioid intraoperatively than African and Indian children, under standardized anesthesia for cleft surgeries. Further research is necessary to elucidate the mechanisms underlying these group differences.
-
Paediatric anaesthesia · Jul 2012
Biography Historical ArticleToivo Suutarinen--father of Finnish pediatric anesthesia.
-
Paediatric anaesthesia · Jul 2012
Is ethnicity associated with morphine's side effects in children? Morphine pharmacokinetics, analgesic response, and side effects in children having tonsillectomy.
To examine whether morphine pharmacokinetics (PK) and/or genetic polymorphisms in opioid-related genes, underlie differences in analgesic response and side effects to morphine in Latino (L) vs non-Latino Caucasian (NL) children. ⋯ We found statistically significant differences in the occurrence of side effects after morphine administration between L and NL children. Neither differences in morphine or metabolite concentrations, nor the genetic polymorphisms examined explain these findings. Studies are needed to further investigate reasons for the increase in morphine side effects by Latino ethnicity.
-
Paediatric anaesthesia · Jul 2012
Spinal anesthesia for noncardiac surgery in infants with congenital heart diseases.
To compare hemodynamic parameters in infants with congenital heart disease (CHD) undergoing noncardiac surgery (NCS) under awake spinal anesthesia (SA) with controls without CHD also undergoing SA. ⋯ These preliminary findings show that hemodynamic parameters in infants with CHD undergoing NCS under awake SA are not different from controls without CHD and that SA appears to be safe in infants with CHD.